Publications 2021

Chai XN, Ludwig FA, Müglitz A, Schaefer M, Yin HY, Brust P, Regenthal R, Krügel U
Validation of an LC-MS/MS Method to Quantify the New TRPC6 Inhibitor SH045 (Larixyl N-methylcarbamate) and Its Application in an Exploratory Pharmacokinetic Study in Mice.
Pharmaceuticals (Basel) 2021; 14(3): 0
ISSN 1424-8247
IF: bisher wurde noch kein IF ermittelt

Chen J, Haase N, Haange SB, Sucher R, Münzker J, Jäger E, Schischke K, Seyfried F, von Bergen M, Hankir MK, Krügel U, Fenske WK
Roux-en-Y gastric bypass contributes to weight loss-independent improvement in hypothalamic inflammation and leptin sensitivity through gut-microglia-neuron-crosstalk.
Mol Metab 2021; 48(): 101214
ISSN 2212-8778
IF: bisher wurde noch kein IF ermittelt

Grohmann M, Schumacher M, Günther J, Singheiser SM, Nußbaum T, Wildner F, Gerevich Z, Jabs R, Hirnet D, Lohr C, Illes P, Schmalzing G, Franke H, Hausmann R
BAC transgenic mice to study the expression of P2X2 and P2Y1 receptors.
Purinergic Signal 2021; 0: 0
ISSN 1573-9538
IF: bisher wurde noch kein IF ermittelt

Illes P, Müller CE, Jacobson KA, Grutter T, Nicke A, Fountain SJ, Kennedy C, Schmalzing G, Jarvis MF, Stojilkovic SS, King BF, Di Virgilio F
Update of P2X receptor properties and their pharmacology: IUPHAR Review 30.
Br J Pharmacol 2021; 178(3): 489-514
ISSN 0007-1188
IF: 8.739

Illes P, Verkhratsky A, Tang Y
Surveilling microglia dampens neuronal activity: operation of a purinergically mediated negative feedback mechanism.
Signal Transduct Target Ther 2021; 6(1): 160
ISSN 2095-9907
IF: bisher wurde noch kein IF ermittelt

Klein N, Kuntz T, Dhein S
Avoiding implantation of a cardioverter-defibrillator by bridging with wearable defibrillator vest.
Herz 2021; 46(2): 172-177
ISSN 0340-9937
IF: 1.443

Rühl P, Rosato AS, Urban N, Gerndt S, Tang R, Abrahamian C, Leser C, Sheng J, Jha A, Vollmer G, Schaefer M, Bracher F, Grimm C
Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors.
Sci Rep 2021; 11(1): 8313
ISSN 2045-2322
IF: bisher wurde noch kein IF ermittelt

Tang Y, Illes P
Tribute to Prof. Geoffrey Burnstock: his contribution to acupuncture.
Purinergic Signal 2021; 17(1): 71-77
ISSN 1573-9538
IF: bisher wurde noch kein IF ermittelt

Zhao YF, Tang Y, Illes P
Astrocytic and Oligodendrocytic P2X7 Receptors Determine Neuronal Functions in the CNS.
Front Mol Neurosci 2021; 14(): 641570
ISSN 1662-5099
IF: bisher wurde noch kein IF ermittelt

Breitinger U, Weinländer K, Pechmann Y, Langlhofer G, Enz R, Becker CM, Sticht H, Kneussel M, Villmann C, Breitinger HG
A proline-rich motif in the large intracellular loop of the glycine receptor alpha1 subunit interacts with the Pleckstrin homology domain of collybistin.
J Adv Res 2021; 29: 95-106
ISSN 2090-1232
IF: 10.479
 
Gaul S, Schaeffer KM, Opitz L, Maeder C, Kogel A, Uhlmann L, Kalwa H, Wagner U, Haas J, Behzadi A, Pelegrin P, Boeckel JN, Laufs U
Extracellular NLRP3 inflammasome particles are internalized by human coronary artery smooth muscle cells and induce pro-atherogenic effects.
Sci Rep 2021; 11(1): 15156
ISSN 2045-2322
IF: bisher wurde noch kein IF ermittelt
 
Hausmann R, Franke H, Schmalzing G
How Prof. Burnstock s enthusiasm supported P2 receptor research in Germany.
Purinergic Signal 2021; 17(1): 139-140
ISSN 1573-9538
IF: 3.765
 
Huang Z, Xie N, Illes P, Di Virgilio F, Ulrich H, Semyanov A, Verkhratsky A, Sperlagh B, Yu SG, Huang C, Tang Y
From purines to purinergic signalling: molecular functions and human diseases.
Signal Transduct Target Ther 2021; 6(1): 162
ISSN 2095-9907
IF: 18.187
 
Karimov M, Schulz M, Kahl T, Noske S, Kubczak M, Gockel I, Thieme R, Büch T, Reinert A, Ionov M, Bryszewska M, Franke H, Krügel U, Ewe A, Aigner A
Tyrosine-modified linear PEIs for highly efficacious and biocompatible siRNA delivery in vitro and in vivo.
Nanomedicine 2021; 36: 102403
ISSN 1549-9634
IF: 6.458
 
Leser C, Keller M, Gerndt S, Urban N, Chen CC, Schaefer M, Grimm C, Bracher F
Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3.
Eur J Med Chem 2021; 210: 112966
ISSN 0223-5234
IF: 6.514
 
Li J, Zhang Y, Illes P, Tang Y, Rubini P
Increasing Efficiency of Repetitive Electroacupuncture on Purine- and Acid-Induced Pain During a Three-Week Treatment Schedule.
Front Pharmacol 2021; 12: 680198
ISSN 1663-9812
IF: 5.810
 
Lin SS, Tang Y, Illes P, Verkhratsky A
The Safeguarding Microglia: Central Role for P2Y 12 Receptors.
Front Pharmacol 2021; 11: 627760
ISSN 1663-9812
IF: 5.810
 
Müller M, Gerndt S, Chao YK, Zisis T, Nguyen ONP, Gerwien A, Urban N, Müller C, Gegenfurtner FA, Geisslinger F, Ortler C, Chen CC, Zahler S, Biel M, Schaefer M, Grimm C, Bracher F, Vollmar AM, Bartel K
Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth.
Cell Chem Biol 2021; 0: 0
ISSN 2451-9456
IF: bisher wurde noch kein IF ermittelt
 
Pacheco-López G, Pérez-Morales M, Guzmán-Ramos KR, Figueroa JD, Krügel U, Bravo JA
Editorial: Obesogenic Environmental Conditions Affect Neurodevelopment and Neurodegeneration.
Front Neurosci 2021; 15(): 724503
ISSN 1662-4548
IF: bisher wurde noch kein IF ermittelt
 
Verkhratsky A, Illes P, Tang Y, Semyanov A
The anti-inflammatory astrocyte revealed: the role of the microbiome in shaping brain defences.
Signal Transduct Target Ther 2021; 6(1): 150
ISSN 2095-9907
IF: 18.787
 
Wang T, Ulrich H, Semyanov A, Illes P, Tang Y
Optical control of purinergic signaling.
Purinergic Signal 2021; 0: 0
ISSN 1573-9538
IF: 3.765
 
Zwirner J, Lier J, Franke H, Hammer N, Matschke J, Trautz F, Tse R, Ondruschka B
GFAP positivity in neurons following traumatic brain injuries.
Int J Legal Med 2021; 0: 0
ISSN 0937-9827
IF: 2.686