Publications 2017

Hankir MK, Seyfried F, Hintschich CA, Diep TA, Kleberg K, Kranz M, Deuther-Conrad W, Tellez LA, Rullmann M, Patt M, Teichert J, Hesse S, Sabri O, Brust P, Hansen HS, de Araujo IE, Krügel U, Fenske WK
Gastric Bypass Surgery Recruits a Gut PPAR-alpha-Striatal D1R Pathway to Reduce Fat Appetite in Obese Rats. Cell Metab 2017 Feb 7; 25(2): 335-344

Drabe M, Rullmann M, Luthardt J, Boettcher Y, Regenthal R, Ploetz T, Becker GA, Patt M, Schinke C, Bergh FT, Zientek F, Hilbert A, Brech A, Fenske W, Hankir MK, Sabri O, Hesse S
Serotonin transporter gene promoter methylation status correlates with in vivo prefrontal 5-HTT availability and reward function in human obesity. Transl Psychiatry 2017 Jul 4; 7(7): e1167. doi: 10.1038/tp.2017.133.

Passamonti L, Luijten M, Ziauddeen H, Coyle-Gilchrist ITS, Rittman T, Brain SAE, Regenthal R, Franken IHA, Sahakian BJ,Bullmore ET, Robbins TW, Ersche D.
Atomoxetine effects on attentional bias to drug-related cues in cocaine dependent individuals. Psychopharmacocogy (Berl). 2017 Aug; 234(15):2289-2297.

Petersen B, Busch T, Noreikat K, Homeister L, Regenthal R, Kaisers UX.
Search for an animal model to investigate selective pulmonary vasodilation. Lab Anim. 2017 Aug; 51(4): 376-387

Brinkman DJ, Tichelaar J, Schutte T, Benemei S, Böttiger y, Chamontin B, Christiaens T, Likic R,Maiulaitis R, Marandi T, Monteiro EC, Papaioannidou P, Pers YM, Pontes C, Raskovic A, Regenthal R, Sanz EJ, Tamba BI,Wilson K, Vries T, Richir MC, Agtmael MV; Working Group Research on CPT Education on the European Association for Clinical Pharmacology and Therapeutics (EACPT).
Essential competencies in prescribing: A first european cross-sectional study among 895 final-year medical students. Clin Pharmacol Ther. 2017 Feb; 101(2):281-289.

Helmschrodt C, Höbel S, Schöniger S, Bauer A, Bonicelli J, Gringmuth M, Fietz SA, Aigner A, Richter A, Richter F.
Polyethylenimine Nanoparticle-Mediated siRNA Delivery to Reduce alpha-Synuclein Expression in a Model Of Parkinson's Disease. Mol Ther Nucleic Acids. 2017 Dec 15; 9:57-68.

Sönnichsen R, Hennig L, Blaschke V, Winter K, Körfer J, Hähnel S, Monecke a, Wittekind C, Jansen-Winkeln B, Thieme R, Gockel I, Grosser K, Weimann A, Kubick C,Wiechmann V, Aigner A, Bechmann I, Lordick F, Kallendrusch S.
Individual Susceptibility Analysis Using Patient-derived slice Cultures of Colorectal Carcinoma. Clin Colorectal Cancer. 2017 Nov 21 pii:S1533-0028(17)30255-4. doi:10.1016/j.clcc.2017.11.002.

Tietze S, Schau I, Michen S, Ennen F, Janke A, Schackert G, Aigner A, Appelhans D, Temme A.
A Poly(Propyleneimine) Dendrimer-Based Polyplex-system for Single-Chain Antibody-Mediated Targeted Delivery and Cellular Uptake of siRNA. Small. 2017 Jul; 13(27). doi: 10.1002/smll.201700072.

Przybylski S, Gasch M, Marschner a, Ebert M,Ewe A, Helmig G, Hilger N, Fricke S, Rudzock S, Aigner A, Burckhardt J.
Influence of nanoparticle-mediated transfection on proliferation of primary immune cells in vitro and in vivo. PLoS One. 2017 May 2; 12(5):e0176517. doi: 10.1371/journal.pone.0176517.

Schwabe K, Ewe A, Kohn C, Loth T,Aigner A, Hacker MC, Schulz-Siegmund M.
Sustained delivery of siRNA poly- and lipopolyplexes from porous macromer-crosslinked gelatin gels. Int J Pharm. 2017 Jun 30; 526(1-2):178-187. doi:10.1016/ijpharm.2017.04.065.

Burkhart A, Andresen TL, Aigner A, Thomsen LB, Moos T.
Transfection of primary brain capillary endothelial cells for protein synthesis and secretion of recombinant erythropoitin: a strategy to enable protein delivery to the brain. Cell Mol Life Sci 2017 Jul; 74(13): 2467-2485.

Hermanns C, Hampl V, Holzer K, Aigner A,Penkava J, Frank N, Martin DE, Maier KC, Waldburger N, Roessler S, Goppelt-Struebe M, Akrap I, Thavamani A, Singer S, Nordheim A, Gudermann T, Muehlich S.
The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma. Oncogene. 2017 Jun 15; 36(24): 3464-3476.

Kunz-Schughart LA, Dubrovska A, Peitzsch C, Ewe A, Aigner A, Schellenburg S, Muders MH, Hampel S, Cirillo G, Iemma F, Tietze R, Alexiou C, Stephan H, Zarschler K, Vittorio O, Kavallaris M,Parak WJ, Mädler L, Pokhrel S.
Nanoparticles for radiooncology: mission, vision, challenges. Biomaterials. 2017 Mar;120:155-184.

Frömberg A, Rabe M, Oppermann H, Gaunitz F, Aigner A.
Analysis of cellular and molecular effects upon inhibition of SATB1 in glioblastoma cells. BMC Cancer. 2017 Jan 3; 17(1):3

Escher BI, Hackermüller J, Polte T, Scholz S, Aigner A, Altenburger R, Böhme A, Bopp SK, Brack W, Busch W, Chadeau-Hyam M, Covaci A, Eisenträger A, Galligan JJ, Garcia-Reyero N, Hartung T, Hein M, Herberth G, Jahnke A, Kleinjans J, Klüver N,Krauss M, Lamoree M, Lehmann I, Luckenbach T, Miller GW, Müller A, Phillips DH, Reemtsma T, Rolle-Kampczyk U, Schürmann G, Schwikowski B, Tan YM, Trump S, Walter-Rohde S, Wambaugh JF.
From the exposome to mechanistic understanding of chemical-induced adverse effects. Environ Int. 2017 Feb; 99:97-106.

Merz L, Höbel S, Kallendrusch S, Ewe A, Bechmann I, Franke H, Merz F,Aigner A.
Tumor tissue slice cultures as a platform for analyzing tissue-penetration and biological activities of nanoparticles. Eur J Pharm Biopharm. 2017 Mar;112:45-50.

Ewe A, Panchal O, Pinnapireddy SR, Bakowsky U, Przybylski S, Temme A,Aigner A.
Liposome-polyethylenimine complexes (DPPC-PEI lipopolyplexes) for therapeutic siRNA delivery in vivo. Nanomedicine. 2017 Jan; 13(1):209-218.

Ewe A, Höbel S, Heine C, Merz L, Kallendrusch S, Bechmann I, Merz F, Franke H, Aigner A.
Optimized polyethylenimine (PEI)-based nanoparticles for siRNA delivery, analyzed in vitro and in an ex vivo tumor tissue slice culture model. Drug Deliv Transl Res. 2017 Apr;7(2):206-216.