Publications 2021

Borchardt H, Ewe A, Morawski M, Weirauch U, Aigner A
miR24-3p activity after delivery into pancreatic carcinoma cell lines exerts profound tumor-inhibitory effects though distinct pathways of apoptosis and autophagy induction
Cancer Lett. 2021; 503;174-184

Chai XN, Ludwig FA, Müglitz A, Schaefer M, Yin HY,Brust O, Regenthal R, Krügel U
Validation of an LC-MS/MS Method to Quantify the New TRPC6 Inhibitor SH045 (Larixyl N- methylcarbamate) and Its Application in an Exploratory Pharmacokinetic Study in Mice
Pharmaceuticals (Basel) 2021; 14(3): 259

Entzian K, Aigner A
Drug Delivery by Utrasound-Responsive Nanocarriers for Cancer Treatment.
Pharmaceutics 2021; 13(8): 1135

Gutsch D, Jenke R, Büch T, Aigner A
Inhibition of HER Receptors Reveals Distinct Mechanisms of Compensatory Upregulation of Other HER Family Members: Basis for Acquired Resistance and for Combination Therapy
Cells 2021; 10(2): 272

Jenke R, Reißing N, Hansen FK, Aigner A, Büch T
Anticancer Therapy with HDAC Inhibitors: Mechanism-Based Combination Strategies and Future Perspectives.
Cancers (Basel) 2021; 13(4): 634

Karimov M, Appelhans D, Ewe A, Aigner A
The combined disulfide cross-linking and tyrosine-modification of very molecular weight linear PEI synergistically enhances transfection efficacies and improves biocompatibility.
Eur J Pharm Biopharm 2021; 161:56-65

Karimov M, Schulz M,Kahl T, Noske S, Kubczak M, Gockel I, Thieme R, Büch T, Reinert A, Ionov M,Bryszewska M, Franke H, Krügel U, Ewe A, Aigner A
Tyrosine-modified linear PEIs for highly efficacious and biocompatible siRNA delivery in vitro and in vivo
Nanomedicine 2021; 36:102403

Regenthal R, Rong P, Krügel U
Nutraceuticals in mental diseases - Bridging the gap between traditional use and modern pharmacology.
Curr Opin Pharmacol 2021;Dec 61: 62-68

Schellenberg LM, Regenthal R, Abraham G
The Rho kinase (ROCK) inhibitor Y-27632 reduces the beta2-adenoreceptor density but enhance cAMP formation in primary equine bronchial epithelial cells.
Eur J Pharmacol 2021; 907:174323

Schoeller C, Hoffmann S, Adolph S, Regenthal R, Abraham G
Expression of muscarinic acetylcholine receptors in turkey cardiac chambers
Res Vet Sci 2021; 136:602-608

Schulz-Siegmung M, Aigner A
Nucleic acid delivery with extracellular vesicles.
Adv Drug Deliv Rev 2021; 173: 89-111

Jugel W, Aigner A, Michen S, Hagstotz A, Ewe A, Appelhans D, Schackert G, Temme A, Tietze S
Targeted RNAi of BIRC5/Survivin Using Antibody-Conjugated Poly(Propylene Imine)-Based Polyplexes Inhibits Growth of PSCA-Positive Tumors.
Pharmaceutics 2021; 13(5):676

Kemper M, Schiecke A, Maar H, Nikulin S, Poloznikov A, Galatenko V, Tachezy M, Gebauer F, Lange T, Riecken K, Tonevitsky A, Aigner A, Izbicki J, Schumacher U, Wicklein D
Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression.
J Exp Clin Cancer Res 2021; 40(1): 214

Kubczak M, Michlewska S, Bryszewska M, Aigner A , Ionov M
Nanoparticles for local delivery of siRNA in lung therapy.
Adv Drug Deliv Rev 2021; 179: 114038

Lewis CA, Mueller K, Zsido RG, Reinelt J, Regenthal R, Okon-Singer H, Forbes EE, Villringer A, Sacher J
A single dose of escitalopram blunts the neutral response in the thalamus and caudate during monetary loss.
J Psychiatry Neurosci 2021; 46(3): 319-327

Molloy EN, Mueller K, Beinhölzl N, Blöchl M, Piecha FA, Pampel A, Steele CJ, Scharrer U, Zheleva G, Regenthal R, Sehm B, Nikulin VV, Möller HE, Villringer A, Sacher J
Modulation of premotor cortex response to sequence motor learning during escitalopram intake.
J Cereb Blood Flow Metab 2021; 41(6): 1449-1462

Molloy EN, Zsido RG, Piecha FA, Beinhölzl N, Scharrer U, Zheleva G, Regenthal R, Sehm B, Nikulin VV, Möller HE, Villringer A, Sacher J, Mueller K
Decreased thalamo-cortico connectivity during an implicit sequence motor learning task and 7 days escitalopram intake.
Sci Rep 2021; 11(1): 15060

Nazarova I, Slyusarenko M, Sidina E, Nikiforova N, Semiglazov V, Semiglazova T, Aigner A, Rybakov E, Malek A
Evalution of Colon-Specific Plasma Nanovesicles as New Markers of Colorectal Cancer.
Cancers (Basel) 2021; 13(15):3905

O Callagham C, Hezemans FH, Ye R, Rua C, Jones PS, Murley AG, Holland N, Regenthal R, Tsvetanov KA, Wolpe N, Barker RA, Williams-Gray CH, Robbins TW, Passamonti L, Rowe JB
Locus coeruleus integrety and the effect of atomoxetine on response inhibition in Parkinsons disease.
Brain 2021; 144: 2513-2526

Offermann A, Kang D, Watermann C, Weingart A, Hupe MC, Saraji A, Stegmann-Frehse J, Kruper R, Schüle R, Pantel K, Taubert H, Duensing S, Culig Z, Aigner A, Klapper W, Jonigk D, Kühnel PM, Merseburger AS, Kirfel J, Sailer V, Perner S
Analysis of tripartite motif (TRIM) family gene expression in prostate cancer bone metastases.
Carcinogenesis 2021; 42(12): 1475-1484

Schellenberg LM, Bonicelli J, Hochheim I, Regenthal R, Abraham G
Corrigendum to "Presence and function of beta-adrenergic receptors in primary equine bronchial epithelia cells"
Pulm Pharmacol Ther 2021; 71:102093

Schoeller C, Hoffmann S, Adolph S, regenthal R, Abraham G
Corrigendum to "Expression of muscarinic acetylcholine receptors in turkey cardiac chambers
Res Vet Sci 2021; 141: 145

Schreyer L, Mittermeier C, Franz MJ, Meier MA, Martin DE, Maier KC, Huebner K, Schneider-Stock R, Singer S, Holzer K, Fischer D, Ribback S, Liebl B, Gudermann T, Aigner A, Muehlich S
Tetrascrition Factors (MRTFs), Controls HCC Growth and Senescence
Cancers (Basel) 2021; 13(21):5373

Zhukovsky P, Morein-Zamir S, Ziauddeen H, Fernandez-Egea E, Meng C, Regenthal R, Sahakian BJ, Bullmore ET, Robbins TW, Dalley JW, Ersche KD
Prefrontal Cortex Activation and Stopping Performance Underlie the Beneficial Effects of Atomoxetine on Response Inhibition in Healthy Volunteers and Those With Cocoain Use Disorder
Biol Psychiatry Cogn Neurosci Neuroimaging 2021;