Publications 2022

Baumann F,Paul T, Wassersleben S, Regenthal R, Enke D, Aigner A
Characterization of Drug Release from Mesoporous SiO(2)-Based Membranes with Variable Pore Structure and Geometry
Pharmaceutics 2022; 14(6): 1184

Borchardt H, Kogel A, Kalwa H,Weirauch U, Aigner A
Therapeutic miR-506-3p Replacement in Pacreatic Carcinoma Leads to Multiple Effects including Autophagy, Apoptosis, Senescense, and Mitochondrial Alterations In Vitro and In Vivo
Biomedicines 2022; 10(7): 1692

Friedrich M, Aigner A
Therapeutic siRNA: State-of-Art and Future Perspectives.
BioDrugs 2022; 36(5): 549-571

Noske S, Karimov M, Hansen M, Zatula N, Ewe A, Aigner A
Non-viral siRNA transfection of primary mesenchymal stromal cells (MSCs): Assessment of tyrosine-modified PEI and PPI efficacy and biocompatibility.
Int J Pharm 2022; 612: 121359

Chai XN, Ludwig FA, Müglitz A, Gong Y, Schaefer M, Regenthal R, Krügel U
A Pharmacokinetic and Metabolism Study of the TRPC6 Inhibitor SH045 in Mice by LC-MS/MS.
Int J Mol Sci 2022; 23(7): 3635

Friedrich M, Pfeifer G, Binder S, Aigner A, Vollmer Barbosa P, Makert GR, Fertey J, Ulbert S, Bodem J, König EM, Geiger N, Schambach A, Schilling E, Buschmann T, Hauschildt S, Koehl U, Sewald K
Selection and Validation of siRNAs Preventing Uptake and Replication of SARS-CoV-2
Front Bioeng Biotechnol 2022; 2: 10

Hezemans FH, Wolpe N, O'Callaghan C, Ye R, Rua C, Jones PS, Murley AG, Holland N, Regenthal R, Tsvetanov KA, Barker RA, Williams-Gray CH, Robbins TW, Passamonti L, Rowe JB
Noradrenergic deficits contribute to apathy in Parkinson's disease through the precision of expected outcomes.
PLoS Comput Biol 2022; 18: 1371

Jugel W, Tietze S, Daeg J, Appelhans D, Broghammer F, Aigner A, Karimov M, Schackert G, Temme A
Targeted Transposition of Minicircle DNA Using Single-Chain Antibody Conjugated Cyclodextrin-Modified Poly (Propylene Imine) Nanocarriers.
Cancers (Basel) 2022; 14(8): 1925

Kubczak M, Michlewska S, Karimov M, Ewe A, Noske S, Aigner A, Bryszewska M, Ionov M
Unmodified and tyrosine-modified polyethylenimines as potential carriers for siRNA: Biophysical characterization and toxicity.
Int J Pharm 2022; Febr 25; 614: 121468

Mirna M, Paar V, Topf A, Kraus T, Sotlar K, Aigner A, Ewe A, Watzinger S, Podesser BK, Hackl M, Pistulli R, Hoppe UC, Kiss A, Lichtenauer M
A new player in the game. treatment with antagomiR-21a-5p significantly attenuates histological and echocardiographic effects of experimental autoimmune myocarditis.
Cardiovasc Res 2022; 29: 556-572

Mitrach F, Schmid M, Toussaint M, Dukic-Stefanovic S, Deuther-Conrad W, Franke H, Ewe A, Aigner A, Wölk C, Brust P, Hacker MC, Schulz-Siegmund M,
Amphiphilic Anionic Oligomer-Stabilized Calcium Phospate Nanoparticles with Prospects in siRNA Delivery via Convection-Enhanced Delivery.
Pharmaceutics 2022; 14: 326

Remy J, Linder B, Weirauch U, Day BW, Stringer BW, Herold-Mende C, Aigner A, Krohn K, Kögel D
STAT3 Enhances Sensitivity of Glioblastoma to Drug-Induced Autophagy-Dependent Cell Death.
Cancers (Basel) 2022; 14(2): 339

Rode M, Nenoff K, Wirkner K, Horn K, Teren A, Regenthal R, Loeffler M, Thiery J, Aigner A, Pott J, Kirsten H, Scholz M
Impact of medication on blood transcription reveals off-target regulations of beta-blockers.
PLos One 2022; 17(4):1932

Schellenberg LM, Regenthal R, Abraham G
Corrigendum to:"The Rho kinase (ROCK) inhibitor Y-27632 reduces the beta 2-adrenoceptor density but enhance cAMP formation in primary equine bronchial epithelial cells"[Eur J Pharmacol 2021 Sept 15; 907: 174323].
Eur J Pharmacol 2022; 915: 174724

Schinke C, Rullmann M, Luthardt J, Drabe M, Preller E, Becker GA, Patt M, Regenthal R, Zientek F, Sabri O, Then Bergh F, Hesse S
HPA Axis Resonsiveness Associates with Central Serotonin Transporter Availability in Human Obesity and Non-Obesity Controls
Brain Sci 2022; 12(11): 1430

Ye R, Mazibuko N, Teichert J, Regenthal R, Kehagia AA, Mehta MA
Mapping the effects of atomoxetine during response inhibition across cortical territories and the locus coeruleus.
Psychopharmacology 2022; 239: 365-376

Zsido RG, Molloy EN, Cesnaite E, Zheleva G, Beinhölzl N, Scharrer U, Piecha FA, Regenthal R, Villringer A, Nikulin VV, Sacher J
One-week escitalopram intake alters the excitation-inhibition balance in the healthy female brain
Hum Brain Mapp 2022; 43: 1868-1881