Project Area Z comprises four purely methodologically oriented subprojects that assume service functions or administrative tasks and support all subprojects equally. In the 3rd AP, Z3 will take over all routine syntheses and the analysis of GAG derivatives as well as the generation of aEZM. Project Z4 (M. von Bergen) provides the TRR 67 with essential technology platforms for proteomics for the qualitative and quantitative analysis of proteins from cellular test systems and animal models, as in previous funding periods.