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Prof. Dr. Annette Beck-Sickinger


Principal Investigator A4

Prof. Dr. Annette Beck-Sickinger,
Professor of Biochemistry and Bioorganic Chemistry

Universität Leipzig
Faculty of Biosciences, Pharmacy and Psychology
Institute of Biochemistry
Brüderstraße 34
04103 Leipzig

Phone: +49 (0)341 97-36900
Fax: +49 (0)341 97-36909

E-Mail: beck-sickinger@uni-leipzig.de

Curriculum Vitae

1986
Diploma in Chemistry (University of Tübingen)
1988
Research fellow at Scripps Clinic and Research Foundation, LaJolla (R. A. Houghten)
1990
Diploma in Biology (University of Tübingen)
1989
Doctorate in Organic Chemistry (University of Tübingen)
1990 – 1991
Postdoctorate at ETH Zürich (Laboratory of Biochemistry, E. Carafoli)
1992
Research fellow at Rigshospitalet Kopenhagen (T. W. Schwartz)
1995
Venia legendi for biochemistry (University of Tübingen)
1996 – 1999
Assistant professor of Pharmaceutical Biochemistry at ETH Zürich
since 1999
Professor of Biochemistry and Bioorganic Chemistry, Universität Leipzig
since 2002 Speaker of Collaborative Research Centre (SFB) 610: "Variation in protein conformation: cell biological and pathological relevance"
since 2004Board member of the German Chemical Society (Gesellschaft Deutscher Chemiker (GDCh)), Vice president 2006 – 2008
since 2004Member of the DFG panel "Biochemistry"
since 2008Chairwoman of the DFG panel 201 "Basics in Biology and Medicine"
since 2009Member of the Saxonian Academy of Sciences
 2010 George Cornell Lecture, Universität Toronto, Kanada
seit 2012
Mitglied der Nationalen Akademie der Wissenschaften Leopoldina, Sektion Chemie
seit 2015
Mitglied des Senates für Evaluation der Leibniz-Gemeinschaft
2016 
Takeda-Vorlesung, Takeda Science Foundation, Osaka
2016
Wissenschaftspreis Leipzig

Publication 

[1]   
Pagel M, Hassert R, Braun K, Wiessler M, Beck-Sickinger AG. Multifunctional Peptide Coating Synergistically Improves Cell Adhesion on Titanium. Angew Chem Int Ed Engl. 2016, 55:4826-30.
[2]Kaiser A, Müller P, Zellmann T, Scheidt HA, Thomas L, Bosse M, Meier R, Meiler J, Huster D, Beck-Sickinger AG, Schmidt P. Unwinding of the C-Terminal Residues of Neuropeptide Y is critical for Y? Receptor Binding and Activation. Angew Chem Int Ed Engl. 2015, 54:7446-9.
[3]Mäde V, Babilon S, Jolly N, Wanka L, Bellmann-Sickert K, Diaz Gimenez LE, Mörl K, Cox HM, Gurevich VV, Beck-Sickinger AG. Peptide modifications differentially alter G protein-coupled receptor internalization and signaling bias. Angew Chem Int Ed Engl. 2014, 53:10067-71.
[4]Reinhardt U, Lotze J, Zernia S, Mörl K, Beck-Sickinger AG, Seitz O. Peptide-templated acyl transfer: a chemical method for the labeling of membrane proteins on live cells. Angew Chem Int Ed Engl. 2014, 53:10237-41.
[5]Baumann L, Beck-Sickinger AG. Photoactivatable chemokines-controlling protein activity by light. Angew Chem Int Ed Engl. 2013, 52:9550-3.
Heiker JT, Klöting N, Kovacs P, Kuettner EB, Sträter N, Schultz S, Kern M, Stumvoll M, Blüher M, Beck-Sickinger AG. Vaspin inhibits kallikrein 7 by serpin mechanism. Cell Mol Life Sci. 2013, 70:2569-83.
[6]Baumann L, Prokoph S, Gabriel C, Freudenberg U, Werner C, Beck-Sickinger AG. A novel, biased-like SDF-1 derivative acts synergistically with starPEG-based heparin hydrogels and im-proves eEPC migration in vitro. J Control Release. 2012, 162:68-75.
[7]
Khan IU, Zwanziger D, Böhme I, Javed M, Naseer H, Hyder SW, Beck-Sickinger AG. Breast-cancer diagnosis by neuropeptide Y analogues: from synthesis to clinical application. Angew Chem Int Ed Engl. 2010, 49:1155-8. 
[8]
David R, Günther R, Baumann L, Lühmann T, Seebach D, Hofmann HJ, Beck-Sickinger AG. Artificial chemokines: combining chemistry and molecular biology for the elucidation of interleu-kin-8 functionality. J Am Chem Soc. 2008, 130:15311-7.
[9]Haack M, Enck S, Seger H, Geyer A, Beck-Sickinger AG. Pyridone dipeptide backbone scan to elucidate structural properties of a flexible peptide segment. J Am Chem Soc. 2008, 130:8326-36. 

(vollständige Liste: http://www.biochemie.uni-leipzig.de/agbs/)