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Synthesis Club

The 3-day seminar "Synthesis Club" introduces the students in modern synthesis methods, e.g. biodegradable polymers for scaffold applications, carbohydrate production and functionalization.

Schedule

14 February 2011

Chemistry of Polysaccarides and Glycosaminoglycans (Dr. Matthias Schnabelrauch)

 9:00–10:30 Lecture: Structure and Reactivity of Polysaccharides and Glycosami­noglycans

  • Architecture of polysaccharides and glycosaminoglycans (structure, basical structural principles, nomenclature)
  • Properties and extraction of selected naturally present and semisynthetic Polysaccarides and Glycosaminoglycanes
  • Stability, reactivity, and polyfunctionality of polysaccharides – Consequences for a defined reaction control

10:45–12:15 Lecture: Chemical Reactions on Polysaccharides

  • Basic chemical reactions on polysaccarides for the introduction of special functional groups
  • Homogeneous vs. heterogene reaction control
  • Regioselective functionalizations
  • Chemico-physical charakterization of modified polysaccarides

13:30–15:00 Lecture:  Immobilization Reactions on Polysaccharides and Glycosaminoglycans

  • Techniques for covalent binding of low molecularized molecules on polysaccarides
  • Activation and coupling chemistries
  • Possibilities of non-covalent fixations of biological active substances on polysaccarides
  • Covalent fixations polysaccharides to surfaces

15:15–16:45 Lecture:  Synthesis and Properties of Hydrogels and Hydrogel Coatings on the Basis of Polysaccharides

  • Networkable derivatives of polysaccarides
  • Network reactions at polysaccharides and glycosaminoglycans for the production of hydrogelds and hydrogel coating
  • Characterization of hydrogels
  • Properties and applications of hydrogels basing on polysaccarides

Day 2: 15 February 2011

Synthesis and surface modification of polymers for biomedical applications (Prof. Dr. Michaela Schulz-Siegmund, Dr. Michael Hacker)

9:00–10:30 Lecture: Synthesis of Polymers for Biomedical Applications
 
10:45–12:15 Lecture: Surface Modification for Biomedical Applications
 
14:15–15:45 Lab Course (Pharmaceutical Technology/Organic Chemistry)
 
16:00–17:30 Lab Course (Organic Chemistry/Pharmaceutical Technology)

Day 3: 16 February 2011

Carbohydrate Chemistry (Prof. Dr. Athanassios Giannis)

9:00–10:30 Lecture:  Carbohydrate Chemistry
 
10:45–13:15 Lab Course (Pharmaceutical Technology/Organic Chemistry)
 
15:00–17:30 Lab Course (Organic Chemistry/Pharmaceutical Technology)

23 February 2011

10.00–11:30 Written Final Examination

Venues:
14/15 February: Institute of Pharmaceutical Technology, Lecture Hall (Eilenburger Straße 15A, 04317 Leipzig)
16 February: Institute of Organic Chemistry, Room 115 (Johannisallee 29, 04103 Leipzig).

Set up:
Maximum number of participants: 10
Credit points: 2 (graded).

Please register until 26 January by sending an e-mail to Anja Pohl.