BioMat – Bioaktive Systeme für kontrolliert evolutionäre Materialien (Nachwuchsgruppe)

Since 2021
Junior Research Group Leader “Bioactive systems for controlled evolutionary materials”, Interfaculty Centre for Bioactive Matter (bACTmatter), University of Leipzig, Germany

Since 2021
Guest scientist at the Department of Solar Materials (SoMa),
Helmholtz Centre for Environmental Research, Leipzig, Germany

2014 – 2021
Scientist at the Department of Solar Materials (SoMa), Helmholtz Centre for Environmental Research, Leipzig, Germany

2012 – 2014
Post-doctoral Researcher at the Laboratory of Chemical Biotechnology, TU Dortmund University, Dortmund, Germany

2007 – 2012
Dissertation at the Laboratory of Chemical Biotechnology,
TU Dortmund University, Dortmund, Germany

2004 – 2007
Master of Science in Chemical Engineering (M. Sc.) with specialization in Biochemical Engineering, TU Dortmund University, Dortmund, Germany

1999 – 2003
Bachelor in Chemical Engineering (B.E), Shivaji University (P.V.P Institute of Technology), Kolhapur, India

1. Bretschneider L, Heuschkel I, Bühler K, Karande R, Bühler B Rational orthologous pathway and biochemical process engineering for adipic acid production using Pseudomonas taiwanensis VLB120. Metabolic Engineering, accepted
2. Bretschneider L, Heuschkel I, Ahmed A, Bühler K, Karande R, Bühler B
   Characterization of different biocatalyst formats for BVMO-catalyzed cyclohexanone oxidation
   Biotechnology and Bioengineering
3. Salamanca D, Bühler K, Engesser K-H, Schmid A, and Karande R*
   Whole-cell biocatalysis using the Acidovorax sp. CHX100 Δ6HX for the production of ω-hydroxycarboxylic acids from cycloalkanes. New Biotechnology, 2021, 60, 200-206.
4. Heuschkel I, Hanisch S, Volke D, Löfgren E, Hoschek A, Nikel P, Karande R, and Bühler K Continuous production of polycaprolactone monomers from cyclohexanone using engineered Pseudomonas taiwanensis VLB120 biofilms in drip-flow and rotating bed reactors Engineering in Life Sciences, 2021.
5. Bretschneider L, Wegner M, Bühler K, Bühler B, and Karande R
   One-pot synthesis of 6-aminohexanoic acid from cyclohexane using mixed-species cultures
   Microbial Biotechnology, 2020, 1-15
6. Heuschkel I, Dagini R, Karande R, and Bühler K The impact of glass material on growth and biocatalytic performance of mixed-species biofilms in capillary reactors for continuous cyclohexanol production Frontiers in Bioengineering and Biotechnology, 2020, 8, 1090-1100
7. Hoschek A, Heuschkel I, Schmid A, Bühler B, Karande R, and Bühler K
   Mixed-species biofilms for high-cell-density application of Synechocystis sp. PCC 6803 in capillary reactors for continuous cyclohexane oxidation to cyclohexanol
   Bioresource Technology, 2019, 282, 171-178
8. Karande R, Salamanca D, Schmid A, and Buehler K Biocatalytic conversion of cycloalkanes to lactones using an in-vivo cascade in Pseudomonas taiwanensis VLB120 Biotechnology and Bioengineering, 2018, 115, 2, 312-320
9. Karande R, Schmid A, and Buehler K
   Applications of multiphasic microreactors for biocatalytic reactions
   Organic Process Research & Development, 2016, 20, 361-370
10. Karande R°, Halan B°, Schmid A, and Buehler K*
    Segmented flow is controlling the growth of catalytic biofilms in continuous multiphase microreactors
    Biotechnology and Bioengineering, 2014, 111, 1831-1840
    °These authors contributed equally to this work
11. Karande R, Schmid A*, and Buehler K
    Miniaturizing Biocatalysis: Enzyme-catalyzed reactions in an aqueous/organic segmented flow capillary microreactor
    Advanced Synthesis and Catalysis, 2011, 353, 2511-2521

1. WO/2020/052762
   A composition of photoautotrophic microorganisms and chemoheterotrophic microorganisms in a biofilm
   Karande R, Hoschek A, Heuschkel I, Bühler K, and Schmid A
   2018
2. WO/2018/046104
   Microorganisms and a method for the production of lactones and their secondary products by converting cycloalkanes
   Karande R, Salamanca D, Engesser K-H, Buehler K, and Schmid A
   2016
3. WO/2012/152337
   Segmented flow biofilm reactor
   Schmid A, Buehler K, and Karande R
   2010