Publications 2001-2005

Allgaier, C., Durmaz, M., Müller, D., Franke, H., Poelchen, W., Wirkner, K., Illes, P.
Single-cell RT-PCR analysis of N-methyl-D-aspartate receptor subunit expression in rat locus coeruleus neurones.
Naunyn Schmiedebergs Arch Pharmacol 363 (2001) 120-3.

Czizh, B., Illes, P.
P2X receptors and nociception.
Pharmacol Rev 53 (2001) 553-568

Di Virgilio, F., Borea, P.A., Illes, P.
P2 receptors meet the immune system.
Trends Pharmacol Sci 22 (2001) 5-7

Dobrev, D., Graf, E., Wettwer, E., Himmel, H.M., Hala, O., Doerfel, C., Christ, T., Schuler, S., Ravens, U.
Molecular basis of downregulation of G-protein-coupled inward rectifying K(+) current (I(K,ACh) in chronic human atrial fibrillation: decrease in GIRK4 mRNA correlates with reduced I(K,ACh) and muscarinic receptor-mediated shortening of action potentials.
Circulation 104 (2001) 2551-2557

Eschke, D., Scheibler, P., Hess, S., Brand, A., Eger, K., Allgaier, C., Nieber, K.
Effects of a novel adenosine A1 receptor ligand on hypoxia-induced changes of membrane properties and and neurotransmitter release in rat brain.
Neurochem Int 38 (2001) 391-398

Fischer, W., Kittner, H., Regenthal, R., Malinowska, B., Schlicker, E.
Anticonvulsant and sodium channel blocking activity of higher doses of clenbuterol.
Naunyn Schmiedebergs Arch Pharmacol 363 (2001) 182-192

Franke, H., Grosche, J., Schädlich, H., Krügel, U., Allgaier, C., Illes, P.
P2X receptor expression on astrocytes in the nucleus accumbens of rats.
Neuroscience 14 (2001) 421-429

Franke, H., Kittner, H.
Morphological alterations of neurons and astrocytes and changes in emotional behavior in pentylenetetrazol kindled rats.
Pharmacol Biochem Behav 70 (2001) 291-303

Franke, H., Bringmann, A., Pannicke, T., Krügel, U., Grosche, J., Reichenbach, A., Illes, P.
P2 receptors on macroglial cells: functional implications for gliosis.
Drug Dev. Res. 53 (2001) 140-147

Franke, H., Krügel, U, Schmidt, R., Grosche, J., Reichenbach, A., Illes, P.
P2 receptor-types involved in astrogliosis in vivo.
Br J Pharmacol 134 (2001) 1180-1189

Grossmann, M., Dobrev, D., Himmel, H.M., Ravens, U., Kirch, W.
Ascorbic acid-induced modulation of venous tone in humans.
Hypertension 37 (2001) 949-954

Hilbig, H., Franke, H., Bidmon, H., Illes, P.
Nitric oxide synthase isoenzymes during in vitro development of rat neuronal and human non-neuronal cells.
Neurosci Lett 297 (2001) 9-12

Himmel, H.M., Stengel, W., Ravens, U.
Selectivity of blocking of low- versus high-voltage activated calcium currents by the dihydropyridine derivatives Bay E5759 and Bay A4339 in neuroblastomaglioma NG 108-15 cells.
Pharmacol Res 44 (2001) 113-6

Himmel, H.M., Wettwer, E., Lues, I., Beier, N., Jonas, R., Ravens, U.
Three thiadiazinone derivatives, EMD 60417, EMD 66430, and EMD 66398, with class III antiarrhythmic activity but different electrophysiologic profiles.
J Cardiovasc Pharmacol 38 (2001) 438-449

Illes, P., Wirkner, K., Nörenberg, W., Masino, S.A., Dunwidde, T.V.
Interaction between the transmitters ATP and glutamate in the central nervous system. Drug.
Develop. Res., 52 (2001) 76-82

Kittner, H., Krügel, U., Illes, P.
The purinergic P2 receptor antagonist pyridoxalphosphate-6-azophenyl- 2'4'-disulphonic acid prevents both the acute locomotor effects of amphetamine and the behavioural sensitization caused by repeated amphetamine injections in rats.
Neuroscience 102 (2001) 241-243

Köles, L., Wirkner, K., Illes, P.
Modulation of ionotropic glutamate receptor channels.
Neurochem Res 26 (2001) 925-932

Krügel, U., Kittner, H., Franke, H., Illes, P.
Stimulation of P2 receptors in the ventral tegmental area enhances dopaminergic mechanisms in vivo.
Neuropharmacology 40 (2001) 1084-1093

Krügel, U., Kittner, H., Illes, P.
Mechanisms of adenosine 5‘-triphosphate-induced dopamine release in the rat nucleus accumbens in vivo.
Synapse 39 (2001) 222-232

Krügel, U., Bigl, V., Eschrich, K., Bigl, M.
Deafferentation of the septohippocampal pathway in rat as a modell of the metabolic events in Alzheimers Disease.
Int J Dev Neurosci 19 (2001) 263-277

Krügel, U., Kittner, H., Franke H., Illes, P.
Accelerated functional recovery after neuronal injury by P2 receptor blockade.
Eur J Pharmacol 420 (2001) R3-R4

Mager, P.P., Reinhardt, R., Fischer, K.;
Molecular simulation to aid in the understanding of the Ab(1-42) peptide of Alzheimer’s Disease.
Molecular Simulation 26 (2001) 367-379.

Mager, P.P.
The active site of HIV-1 protease.
Med Res Rev 2001 Jul;21(4):348-53

Mager, P.P., Fischer, K.
Simulation of the lipophilic and antigenic cores of the A beta(1-42) peptide of Alzheimer's disease.
Molecular Simulation 27 (2001) 237-242

Mager, P.P.
Molecular simulation of solution conformations of the amyloid beta-peptide A beta(1-42) by a backpropagation neural network model.
Molecular Simulation 27 (2001) 43-+

Narahashi, T., Kuriyama, K., Illes, P., Wirkner, K., Fischer, W., Mühlberg, K., Scheibler, P., Allgaier, C., Minami, K., et. al.
Neuroreceptors and ion channels as targets of alcohol.
Alcohol Clin Exp Res 25 (2001) 182S-188S

Nörenberg, W.; Göbel, I.; Meyer, A.; Cox, S.L.; Starke, K.; Trendelenburg, A.U.
Stimulation of mouse cultured sympathetic neurons by uracil but not adenine nucleotides.
Neuroscience 103 (2001) 227-236

Poelchen, W., Kittner, H.,Sieler, D., Regenthal, R., Preiss, R. , Illes, P.
In vitro tolerance to inhibition by ethanol of NMDA-induced depolarization in locus coeruleus neurons of behaviorally ethanol-tolerant rats.
Neurochem Int 39 (2001) 51-58

Poelchen, W., Sieler, D., Wirkner, K., Illes, P.
Co-transmitter function of ATP in central catecholaminercic neurons of the rat.
Neuroscience 102 (2001) 593-602.

Reinhardt, R., Manaenko, A., Wagner, A., Pissarek, M., Illes, P.
Alterations of purine and pyrimidine nucleotide contents in rat corticoencephalic cell cultures following hypoxia and treatment with openers and blockers of ATP-sensitive potassium channels.
Neurochem. Int., 1143 (2001) 1-7

Schädlich, H., Wirkner, K., Franke, H., Bauer, S., Grosche, J., Burnstock, G., Reichenbach, A., Illes, P., Allgaier, C.
P2X2, P2X2 –2 and P2X5 receptor subunit expression and function in rat thoracolumbal sympathetic neurons.
J Neurochem 79 (2001) 997-1003

Sperlagh, B., Illes, P., Gerevich, Z., Köfalvi, A.
Distinct mechanisms underlying a1 and P2X receptor operated ATP release and contraction in the guinea-pig vas deferens.
Neurochem Res 26 (2001) 951-957

Trendelenburg, A.U.; Nörenberg, W.; Hein, L.; Starke, K.
Alpha2-adrenoceptor-mediated inhibition of cultured sympathetic neurons: changes in alpha2A/D-adrenoceptor-deficient mice.
Naunyn Schmiedebergs Arch Pharmacol 363 (2001) 110-119

Vartian, N., Moskvina, E., Scholze, T., Unterberger, U., Allgaier, C., Boehm, S.
UTP evokes noradrenaline release from rat sympathetic neurons by actviation of protein kinase C.
J Neurochem 77 (2001) 876-885

Allgaier C.
Ethanol sensitivity of NMDA receptors.
Neurochem Int. 2002 Dec;41(6):377-82. Review.

Fischer W.
Anticonvulsant profile and mechanism of action of propranolol and its two enantiomers.
Seizure. 2002 Jul;11(5):285-302.

Fischer W, Franke H, Scheibler P, Allgaier C, Illes P.
AMPA-induced Ca2+ influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry.
Eur J Pharmacol. 2002 Mar 1;438(1-2):53-62.

Franke H, Grosche J, Illes P, Allgaier C.
5,7-Dihydroxytryptamine--a selective marker of dopaminergic or serotonergic neurons?
Naunyn Schmiedebergs Arch Pharmacol. 2002 Oct;366(4):315-8.

Franke H, Schelhorn N, Illes P.
Dopaminergic neurons develop axonal projections to their target areas in organotypic co-cultures of the ventral mesencephalon and the striatum/prefrontal cortex.
Neurochem Int. 2003 Apr;42(5):431-9.

Gaunitz C, Schuttler A, Gillen C, Allgaier C.
Formalin-induced changes of NMDA receptor subunit expression in the spinal cord of the rat.
Amino Acids. 2002;23(1-3):177-82.

Gerevich Z, Wirkner K, Illes P.
Adenosine A2A receptors inhibit the N-methyl-D-aspartate component of excitatory synaptic currents in rat striatal neurons.
Eur J Pharmacol. 2002 Sep 13;451(2):161-4.

Günther A, Manaenko A, Franke H, Dickel T, Berrouschot J, Wagner A, Illes P, Reinhardt R.
Early biochemical and histological changes during hyperbaric or normobaric reoxygenation after in vitro ischaemia in primary corticoencephalic cell cultures of rats.
Brain Res. 2002 Aug 9;946(1):130-8.

Himmel HM, Kiss T, Borvendeg SJ, Gillen C, Illes P.
The arginine-rich hexapeptide R4W2 is a stereoselective antagonist at the vanilloid receptor 1: a Ca2+ imaging study in adult rat dorsal root ganglion neurons.
J Pharmacol Exp Ther. 2002 Jun;301(3):981-6.

Koizumi S, Saito Y, Nakazawa K, Nakajima K, Sawada JI, Kohsaka S, Illes P, Inoue K.
Spatial and temporal aspects of Ca2+ signaling mediated by P2Y receptors in cultured rat hippocampal astrocytes.
Life Sci. 2002 Dec 20;72(4-5):431-42.

Ludewig, R., Preiss, R., Regenthal, R., Illes, P., Kleemann, W.J., Krüger, N. and Schreinicke, G.
Aktuelles zu Arzneimitteln und Giften – Möglichkeiten und Unmöglichkeiten der klinisch-pharmakologischen und –toxikologischen Information von Ärzten und Patienten.
Ärzteblatt Sachsen 2002;11:530-535

Mager PP.
Protein conformation disorders: Preface.
Current Medicinal Chemistry, 2002;9:1716

Mager PP.
Hybrid 3-D QSAR approach using a gerneralized-regression genetic-neural network.
Molecular Simulation. 2002;28(4):377-384

Mager PP.
Backpropagation neural network analysis applied to b-sheet breakers used against Alzheimer´s amyloid aggregation.
Molecular Simulation. 2002;28(3):239-247

Mager PP.
Comparison of neural network and regression models in molecular simulation of relationships between chemical structure and biological activity.
Molecular Simulation. 2002;28(3):287-294

Mager PP, Penke B, Walter R, Harkany T, Härtig W.
Pathological peptide folding in Alzheimer´s disease and other conformational disorders.
Current Medicinal Chemistry, 2002;9:1763-1780

Masino SA, Diao L, Illes P, Zahniser NR, Larson GA, Johansson B, Fredholm BB, Dunwiddie TV.
Modulation of hippocampal glutamatergic transmission by ATP is dependent on adenosine A1 receptors.
J Pharmacol Exp Ther. 2002 Oct;303(1):356-63.

Reinhardt R, Manaenko A, Pissarek M, Wagner A, Illes P.
Alterations of purine and pyrimidine nucleotide contents in rat corticoencephalic cell cultures following metabolic damage and treatment with openers and blockers of ATP-sensitive potassium channels.
Neurochem Int. 2002 Apr;40(5):427-33.

Wirkner K, Köles L, Thümmler S, Luthardt J, Poelchen W, Franke H, Fürst S, Illes P.
Interaction between P2Y and NMDA receptors in layer V pyramidal neurons of the rat prefrontal cortex.
Neuropharmacology. 2002 Mar;42(4):476-88.

Wunderlich H, Beer J, Allgaier C.
Clopidogrel – ein Thrombozytenaggregationshemmer mit Wirkung am P2Y12-Rezeptor.
Med Monatsschr Pharm. 2002 Dec;25(12):425-9.

Borvendeg JS, Al-Khrasani M, Rubini P, Fischer W, Allgaier C, Wirkner K, Himmel HM, Gillen C, Illes P
Subsensitivity of P2X but not vanilloid 1 receptors in dorsal root ganglia of rats caused by cyclophosphamide cystitis.
Eur J Pharmacol, 2003, 474: 71-75.

Borvendeg SJ, Gerevich Z, Gillen C, Illes P.
P2Y receptor-mediated inhibition of voltage-dependent Ca2+ channels in rat dorsal root ganglion neurons.
Synapse, 2003, 47: 159-161

Fischer W, Wirkner K, Weber M, Eberts C, Köles L, Reinhardt R, Franke H, Allgaier C, Gillen C, Illes P
Characterization of P2X3, P2Y1 and P2Y4 receptors in cultured HEK293-hP2X3 cells and their inhibition by ethanol and trichloroethanol.
J. Neurochem, 2003, 85:779-790.

Fischer W, Franke H, Illes P.
Effects of acute ethanol on the Ca2+ response to AMPA in cultred rat cortical GABAergic nonpyramidal neurons.
Alcohol Alcohol, 2003, 38:394-399.

Franke H, Krugel U, Grosche J, Illes P.
Immunoreactivity for glial fibrillary acidic protein and P2 receptor expression on astrocytes in vivo. Drug Development Res, 2003, 59:175-189.

Franke H, Schelhorn N, Illes P
Dopaminergic neurons develop axonal projections to their target areas in organotypic co-cultures of the ventral mesencephalon and the striatum/prefrontal cortex.
Neurochem Int, 2003, 42:431-439.

Franke H, Kittner H, Grosche J, Illes P
Enhanced P2Y1 receptor expression in the brain after sensitisation with d-amphetamine
Psychopharmacology 2003; 167: 187-194.

Fredholm BB, Halldner L, Johansson C, Schulte G, Lövdahl C, Thorén P, Dunwiddie TV, Masino SA, Poelchen W, Diao L, Illes P, Zahniser NR, Valen G, Tokuno S, Sommerschild H, Giménez-Llort L, Fernández-Teruel A, Escorihuela RM, Wiesenfeld-Hallin Z, Xu XJ, Hårdemark A, Herlenius E, Pekny M, Gebré-Medhin S, Brown R, Ollerstam A, Persson AEG, Skøtt O, Johansson B.
Consequences of eliminating adenosine A1 receptors in mice.
Drug Development Research 2003; 58 (4): 350-353

Gebhardt R, Hengstler JG, Muller D, Glockner R, Buenning P, Laube B, Schmelzer E, Ullrich M, Utesch D, Hewitt N, Ringel M, Hilz BR, Bader A, Langsch A, Koose T, Burger HJ, Maas J, Oesch F.
New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures.
Drug Metab Rev. 2003; 35(2-3): 145-213

Hartlage-Rübsamen M, Zeitschel U, Apelt J, Gärtner U, Franke H, Stahl T, Günther A, Schliebs R, Penkowa M, Bigl V, Rossner S.
Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulus-dependent.
Glia 2003; 41(2):169-179

Kittner H, Franke H, Fischer W, Schultheis N, Krügel U, Illes P
Stimulation of P2Y1 receptors causes anxiolytic effects in the rat elevated plus-maze; implications for the involvement of P2Y1 receptor mediated nitric oxide production.
Neuropsychopharmacology 2003; 28: 435-444

Krügel U, Schraft T, Kittner H, Kiess W, Illes P
Basal and feeding-evoked dopamine release in the rat nucleus accumbens is depressed by leptin
European Journal of Pharmacology 2003; 482: 185-187

Krügel U, Kittner H, Franke H, Illes P
Purinergic modulation of neuronal activity in the mesolimbic dopaminergic system in vivo.
Synapse 2003; 47(2):134-142

Krügel U, Seidel B, Spies O, Kittner H, Illes P, Kiess W.
Chronic food restriction alters purinergic receptor mRNA expression in the nucleus accumbens of the rat.
Drug Development Res. 2003; 59 (1): 95-103

Lange-Dohna C, Zeitschel U, Gaunitz F, Perez-Polo JR, Bigl V, Roßner S
Cloning and expression of the rat BACE1 promoter.
Journal of Neuroscience Research 2003; 73 (1): 73-80 

Luthardt J, Borvendeg SJ, Sperlagh B, Poelchen W, Wirkner K, Illes P.
P2Y(1) receptor activation inhibits NMDA receptor-channels in layer V pyramidal neurons of the rat prefrontal and parietal cortex.
Neurochem Int. 2003; 42(2): 161-72

Mager PP
Molecular simulation of chemical structure and biological activity of thromboxane synthase inhibitors by multivariate neural-network analysis.
Molecular Simulation 2003; 29 (1): 71 – 75

Mager PP
A problem if binary molecular substructural variables are used in simulation experiments.
Molecular Simulation 2003; 29 (2): 159 - 166

Mager PP, De Clercq E, Froeyen M, Reinhardt R
Interactions of the dimeric triad of HIV-1 aspartyl protease with inhibitors.
Drug Design and Discovery 2003; 18: 53 – 64

Mager PP.
Hybrid canonical-correlation neural-network approach applied to nonnucleoside HIV-1 reverse transcriptase inhibitors (HEPT derivatives).
Curr Med Chem. 2003; 10(17): 1643-59.

Morl F, Leemhuis J, Lindemeyer K, Grass N, Norenberg W, Meyer DK.
Stimulation of GABAB receptors increases the expression of the proenkephalin gene in slice cultures of rat neocortex.
Naunyn Schmiedebergs Arch Pharmacol. 2003; 367(6): 640-7

Poelchen W, Wirkner K
Ein potentieller biologischer Kampfstoff.
Pharmazeutische Zeitung 2003; (6): 21 – 26

Reinhardt R, Manaenko A, Günther A, Franke H, Dickel T, Garcia de Arriba S, Münch G, Wagner A, Illes P
Early biochemical and histological alterations in rat corticoencephalic cell cultures following metabolic damage and treatment with modulators of mitochondrial ATP-sensitive potassium channels.
Neurochem. Int. 2003; 43: 563-571

Schiffer IB, Gebhard S, Heimerdinger CK, Heling A, Hast J, Wollscheid U, Seliger B, Tanner B, Gilbert S, Beckers T, Baasner S, Brenner W, Spangenberg C, Prawitt D, Trost T, Schreiber WG, Zabel B, Thelen M, Lehr HA, Oesch F, Hengstler JG.
Switching off HER-2/neu in a tetracycline-controlled mouse tumor model leads to apoptosis and tumor-size-dependent remission.
Cancer Research 2003; 63: 7221-7231

Wirkner K, Köles L, Fürst S, Illes P
Modulation of voltage- and ligand-gated ion channels by neuronal P2Y receptors
Drug Development Research 2003; 59 (1): 49-55

Allgaier C, Reinhardt R, Schadlich H, Rubini P, Bauer S, Reichenbach A, Illes P.
Somatic and axonal effects of ATP via P2X but not P2X receptors in rat thoracolumbar sympathetic neurones.
J Neurochem, 2004, 90:359-567.

Allgaier C, Arendt T.
[Galantamine, an acetylcholinesterase inhibitor with various actions],
Med Monatsschr Pharm, 2004, 27:223-227.

Cunha-Reis D, Sebastiao AM, Wirkner K, Illes P, Ribeiro JA.
VIP enhances both pre- and postsynaptic GABAergic transmission to hippocampal interneurones leading to increased excitatory synaptic transmission to CA1 pyramidal cells.
Br J Pharmacol, 2004, 143:733-744.

Fischer W, Kittner H, Regenthal R, Russo E, De Sarro G.
Effects of piracetam alone and in combination with antiepileptic drugs in rodent seizure models.  Neural Transm, 2004, 111:1121-1139.

Fischer W, Kittner H, Regenthal R, De Sarro G.
Anticonvulsant profile of flunarizine and relation to Na+ channel blocking effects.
Basic Clin Pharmacol Toxicol, 2004, 94:79-88.

Gerevich Z, Illes P.
P2Y receptors and pain transmission.
Purinergic Signalling, 2004, 1:3-10.

Gerevich Z, Borvendeg SJ, Schroder W, Franke H, Wirkner K, Norenberg W, Furst S, Gillen C, Illes P.
Inhibition of N-type voltage-activated calcium channels in rat dorsal root ganglion neurons by P2Y receptors is a possible mechanism of ADP-induced analgesia.
J Neurosci, 2004, 24:797-807.

Gunther A, Manaenko A, Franke H, Wagner A, Schneider D, Berrouschot J, Reinhardt R.
Hyperbaric and normobaric reoxygenation of hypoxic rat brain slices - impact on purine nucleotides and cell viability.
Neurochem Int, 2004, 45:1125-1132.

Illes P, Ribeiro JA.
Neuronal P2 receptors of the central nervous system.
Curr Top Med Chem, 2004, 4:831-838.

Illes P, Ribeiro JA.
Molecular physiology of P2 receptors in the central nervous system.
Eur J Pharmacol, 2004, 483:5-17.

Eger K, Hermes M, Uhlemann K, Rodewald S, Ortwein J, Brulport M, Bauer AW, Schormann W, Lupatsch F, Schiffer IB, Heimerdinger CK, Gebhard S, Spangenberg C, Prawitt D, Trost T, Zabel B, Sauer C, Tanner B, Kolbl H, Krugel U, Franke H, Illes P, Madaj-Sterba P, Bockamp EO, Beckers T, Hengstler JG.
4-Epidoxycycline: an alternative to doxycycline to control gene expression in conditional mouse models.
Biochem Biophys Res Commun, 2004, 323:979-986.

Franke H, Krugel U, Grosche J, Heine C, Hartig W, Allgaier C, Illes P.
P2Y receptor expression on astrocytes in the nucleus accumbens of rats.
Neuroscience, 127:431-441.

Franke H, Gunther A, Grosche J, Schmidt R, Rossner S, Reinhardt R, Faber-Zuschratter H, Schneider D, Illes P.
P2X7 receptor expression after ischemia in the cerebral cortex of rats.
J Neuropathol Exp Neurol, 2004, 63:686-699.

Kittner H, Hoffmann E, Krugel U, Illes P.
P2 receptor-mediated effects on the open field behaviour of rats in comparison with behavioural responses induced by the stimulation of dopamine D2-like and by the blockade of ionotrophic glutamate receptors.
Behav Brain Res, 2004, 149:197-208.

Kittner H, Krugel U, Hoffmann E, Illes P.
Modulation of feeding behaviour by blocking purinergic receptors in the rat nucleus accumbens: a combined microdialysis, electroencephalographic and behavioural study.
Eur J Neurosci, 2004, 19:396-404.

Krugel U, Schraft T, Regenthal R, Illes P, Kittner H.
Purinergic modulation of extracellular glutamate levels in the nucleus accumbens in vivo.
Int J Dev Neurosci, 2004, 22:565-570.

Scheibler P, Pesic M, Franke H, Reinhardt R, Wirkner K, Illes P, Norenberg W.
P2X2 and P2Y1 immunofluorescence in rat neostriatal medium-spiny projection neurones and cholinergic interneurones is not linked to respective purinergic receptor function.
Br J Pharmacol, 2004, 143:119-131.

Wirkner K, Gerevich Z, Krause T, Gunther A, Koles L, Schneider D, Norenberg W, Illes P.
Adenosine A2A receptor-induced inhibition of NMDA and GABAA receptor-mediated synaptic currents in a subpopulation of rat striatal neurons.
Neuropharmacology, 2004, 46:994-1007.

Wirkner K, Schweigel J, Gerevich Z, Franke H, Allgaier C, Barsoumian EL, Draheim H, Illes P.
Adenine nucleotides inhibit recombinant N-type calcium channels via G protein-coupled mechanisms in HEK 293 cells; involvement of the P2Y13 receptor-type.
Br J Pharmacol, 2004, 141:141-151.

Wirkner K, Krause T, Koles L, Thummler S, Al-Khrasani M, Illes P.
D1 but not D2 dopamine receptors or adrenoceptors mediate dopamine-induced potentiation of N-methyl-d-aspartate currents in the rat prefrontal cortex.
Neurosci Lett, 2004, 372:89-93.

Caciagli F, Illes P.
First joint Italian–German purine club meeting BProgress in Purinergic Receptor
Pharmacology and Function.
Purinergic Signalling. 2005, 1 (4):297 - 298

Fischer W.
Influence of ethanol on the threshold for electroshock-induced seizures and electrically-evoked hippocampal afterdischarges.
J Neural Transm. 2005 Sep;112(9):1149-63.

Fischer W, Franke H, Gröger-Arndt H, Illes P.
Evidence for the existence of P2Y1,2,4 receptor subtypes in HEK-293 cells: reactivation of P2Y1 receptors after repetitive agonist application.
Naunyn Schmiedebergs Arch Pharmacol, 2005, 371:466-472.

Franke H, Grummich B, Hartig W, Grosche J, Regenthal R, Edwards RH, Illes P, Krugel U.
Changes in purinergic signaling after cerebral injury - involvement of glutamatergic mechanisms?
Int. J. Dev. Neurosci., 2005 Dec 29;]

Franke H., Illes P.
Involvement of P2 receptors in the growth and survival of neurons in the CNS.
Pharmacol Ther, 2005,

Franke H, Klimke K, Brinckmann U, Grosche J, Francke M, Sperlagh B, Reichenbach A, Liebert UG, Illes P.
P2X7 receptor-mRNA and -protein in the mouse retina; changes during retinal degeneration in BALBCrds mice.
Neurochem Int, 2005, 47:235-242.

Garcia de Arriba S, Fengler D, Verdaguer E, García-Jordá E, Pallas M, Camins A, Münch G, Allgaier C
Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity.
Free Radic Biol Med, 2005, in press

Gerevich Z, Müller C, Illes P.
Metabotropic P2Y1 receptors inhibit P2X3 receptor-channels in rat dorsal root ganglion neurons.
Eur J Pharmacol. 2005, 521:34-38.

Guzman SJ, Gerevich Z, Hengstler JG, Illes P, Kleemann W.
P2Y1 receptors inhibit both strength and plasticity of glutamatergic synaptic neurotransmission in the rat prefrontal cortex.
Synapse, 2005, 57:235-238.

Hasko G, Pacher P, Sylvester Vizi E, Illes P.
Adenosine receptor signaling in the brain immune system.
Trends Pharmacol Sci, 2005, 26:511-516.

Jaekel B, Mühlberg K, Garcia de Arriba S, Reichenbach A, Verdaguer E, Pallas M, Camins A, Nörenberg W, Allgaier C.
Neuroprotection associated with alternative splicing of NMDA receptors in rat cortical neurons.
Br J Pharmacol. 2005 Nov 28

Jorda EG, Verdaguer E, Jimenez A, Arriba SG, Allgaier C, Pallas M, Camins A.
Evaluation of the neuronal apoptotic pathways involved in cytoskeletal disruption-induced apoptosis.
Biochem Pharmacol, 2005, 70:470-480.

Jorda EG, Verdaguer E, Canudas AM, Jiménez A, Garcia de Arriba S, Allgaier C, Pallàs M, Camins A.
Implication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium. Neuroscience, 2005, 134:1001-11

Köles L, Fürst S, Illes P.
P2X and P2Y receptors as possible targets of therapeutic manipulations in CNS illnesses. Drug News Perspect, 2005, 18:85-101.

Mager PP, Sanchez L
Variable Subset Selection in the Presence of Flagged Observations and Multicollinear Descriptors in QSAR
Current Computer-Aided Drug Design 2005; 1(2): 163-177

Mager PP, Weber A, Illes P
Quantitative Structure-Activity Relationship Analysis of the Cation Permeability of the P2X2 Channel
Medicinal Chemistry 2005; 1(2): 109-115

Mager PP, Weber A, Walter H, Wirkner K, Illes P
Perspectives in Proteomics: Structural Folds of a Predicted and an Experimentally Determined Cation Channel.
Curr Proteomics 2005; 2(4): 319-324

Pallàs M, Canudas AM, Verdaguer E, Allgaier C, Garcia de Arriba S, Alvira D, Sureda FX, A. Camins A
Inhibitors of cyclin-dependent kinases: potential drugs for the treatment of neurodegenerative disorders?
Current Med Chem – Central Nervous System Agents, 101-109

Sak K, Illes P.
Neuronal and glial cell lines as model systems for studying P2Y receptor pharmacology. Neurochem Int, 2005, 47:401-412.

Steffens M, Huber M, Allgaier C, Feuerstein TJ.
Does the binding duration of a partial α2-adrenoceptor agonist exceed its activation interval at the autoreceptor?
Int J Pharmacol, 2005, 1:299-310.

Wirkner K, Hognestad H, Jahnel R, Hucho F, Illes P.
Characterization of rat transient receptor potential vanilloid 1 receptors lacking the N-glycosylation site N604.
Neuroreport, 2005, 16:997-1001.

Wirkner K, Kofalvi A, Fischer W, Gunther A, Franke H, Groger-Arndt H, Norenberg W, Madarasz E, Vizi ES, Schneider D, Sperlagh B, Illes P.
Supersensitivity of P2X7 receptors in cerebrocortical cell cultures after in vitro ischemia.
J. Neurochem.2005 Dec;95(5):1421-37.

Wirkner K, Stanchev D, Köles L, Klebingat M, Dihazi H, Flehmig G, Vial C, Evans RJ, Furst S, Mager PP, Eschrich K, Illes P.
Regulation of human recombinant P2X3 receptors by ecto-protein kinase C.
J Neurosci, 2005, 25:7734-7742.