“Security check” inside the cell: Self-cleavage as built-in quality control
When cells produce aGPCRs – our cellular force sensors – the receptors split into two parts. It has now been shown that they need assistance to complete this cleavage before being transported to the cell surface, where they detect signals from their surroundings. Image: Yin Kwan Chung with BioRender.com

“Security check” inside the cell: Self-cleavage as built-in quality control

Biochemist Prof. Dr. Annette G. Beck-Sickinger was awarded the Sir Hans Krebs Medal 2025 for her research on peptide receptors. Photo: FEBS

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