May 2019 – Vanderbilt / Leipzig University

Johanna K. S. Tiemann1, Prof. Dr. Vsevolod Gurevich2, Dr. Sandra Berndt2 1. Leipzig University 2. Vanderbilt University The aim of my exchange was to deepen the collaboration between the laboratory of Prof. Peter Hildebrand and Prof. Tina Iverson and Prof. Seva Gurevich and to push the project on the investigation of arrestin interactions with SRC family kinases forward. Arrestin is a key intracellular downstream signaling molecule, mediating G protein-coupled receptors and other proteins such as kinases. Those proteins are involved in tumor progression and metastasis, their study, therefore, of noticeable interest. Especially the interaction of arrestin with kinases, in particular, SRC family kinases is so far barely understood. Through the established

[article written by Dr. Katarina Werneburg Leipzig University / picture: Humboldt-Stiftung/Elbmotion] The Alexander von Humboldt Foundation awarded Prof. Dr. Jens Meiler the highly endowed Alexander von Humboldt Professorship. The 44-year-old is one of the world’s most distinguished researchers in the field of computer-aided drug discovery. The Alexander von Humboldt Professorship is Germany’s most valuable research prize. “I am delighted that the long-standing research partnership between Leipzig University and Vanderbilt University has now culminated in Jens Meiler’s Humboldt Professorship. This will unlock new horizons for Professor Beck-Sickinger’s already highly successful area of research into molecular mechanisms. It will also considerably strengthen our degree program in Pharmacy at the Faculty of Medicine,” commented

Short Report by Johanna Tiemann: Arrestin interaction with SRC family kinases. (Apr. 2019)

The Alexander von Humboldt Foundation awarded Prof. Dr. Jens Meiler