07.-21.08.2020: Virtual Course “Computational methods to study protein structure and dynamics” (Hildebrand, Meiler, Smith, Moretti)

07.-21.08.2020: Virtual Course “Computational methods to study protein structure and dynamics” (Hildebrand, Meiler, Smith, Moretti)

Syllabus – CPBP 8330 – Special Topics in Protein BiochemistryCOMPUTATIONAL METHODS TO STUDY PROTEIN STRUCTURE AND DYNAMICS Course Description:Biomolecules undergo constant motions and fluctuations in their native environment. Many of these motions are directly related to function: Channels have to open or close, transporters change their form to conduct molecules and receptors undergo conformational changes to transmit signals through membranes. Despite that obvious dynamics, biomolecules are still commonly considered as rigid entities that exist in one or only few states. This limitation largely prevents understanding of molecular events that are guided or even ruled by intrinsic flexibility such as ligand binding or protein-protein recognition. Molecular dynamics (MD) simulation is a well-established

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Scientists find human antibodies against COVID-19

Scientists find human antibodies against COVID-19

[article written by Peggy Darius Leipzig University] The COVID 19 pandemic poses a major threat to global health and currently there is little medical response. In addition, there is a lack of a profound understanding of the molecular mechanisms of the body’s immune system. An international team has now succeeded in scientifically describing highly active neutralizing human antibodies against the corona virus SARS-CoV-2. Humboldt Professor Jens Meiler of the University of Leipzig contributed to the study, which has now been published in the scientific journal “Nature”. Highly active neutralizing human antibodies against the coronavirus SARS-CoV-2 can be used for the development of vaccines and can also be used as therapy in

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