October 20-24, 2018; Syllabus – CPBP 8330 – Special Topics in Ligand-Protein Recognition Prof. Dr. Annette G. Beck-Sickinger, Leipzig University, Faculty of Life Sciences, Institute of Biochemistry Date October 20-24, 2018 Venue Departments of Chemistry, Pharmacology, and Biomedical Informatics, Center for Structural Biology, and Institute of Chemical Biology, 465 21st Ave South, BIOSCI/MRBIII, Room 5131, Nashville, TN 37232-8725 The student will become familiar with the synthesis, analysis, chemical modification and biological testing of peptide and protein GPCR ligands. Many ligands of GPCR belong to the family of peptides and proteins. This includes all class B GPCR ligands, e. g. calcitonin, glucagon and the pharmacologically relevant GLP-1, from which modified analogies have