Evaluating scaling of capillary photo-biofilm reactors for high cell density cultivation of mixed trophies artificial microbial consortia

Capillary biofilm reactors (CBRs) are attractive for growing photoautotrophic bacteria as they allow high cell-density cultivation. Here, we evaluated the CBR system’s suitability to grow an artificial consortium composed of Synechocystis sp. PCC 6803 and Pseudomonas sp. VBL120. The impact of reactor material, flow rate, pH, O2, and medium composition on biomass development and long-term biofilm stability at different reactor scales was studied. Silicone was superior over other materials like glass or PVC due to its excellent O2 permeability.

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https://onlinelibrary.wiley.com/doi/10.1002/elsc.202300014

Entropic repulsion of cholesterol-containing layers counteracts bioadhesion

Based on a cooperation with colleagues from Dresden, we newly published a paper in Nature on a new mechanism counteracting bioadhesion by entropic repulsion of orientational fluctuations in cholesterol multilayers. Our results not only reveal this new mechanism of entropic repulsion to be relevant in the surface properties of Collembola, but, also shows the high specificity of the cholesterol chemistry.

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https://www.nature.com/articles/s41586-023-06033-4

Development of a synthesis strategy for sulfamethoxazole derivatives and their coupling with hydrogel microparticles

Click here for the article by Prof. Dr. Tilo Pompe, Veronika Riedl, Matthias Portius, Lara Heiser, Philipp Riedl, Torsten Jakob, Rosa Gehring and Thorsten Berg:

https://research.uni-leipzig.de/bact/wp-content/uploads/2023/05/2023-JMatChemB-SCP-SMX.pdf

Read more: Development of a synthesis strategy for sulfamethoxazole derivatives and their coupling with hydrogel microparticles