The goal of this Integrated Research Training Group (IRTG) is a training program that comprehensively addresses all aspects of current GPCR research. This profile will qualify graduates for an independent career in various acdemic and industrial areas. The doctoral researchers are expected to spend about 5-10% of their time on qualification, which is mainly covered by this program. A comprehensive qualification program will be established comprising four sections: scientific modules, annual summer schools, international laboratory rotations, and professional skills workshops. The SFB1423 depends on interdisciplinary collaboration of the project leaders. That also applies to the research projects of the doctoral researchers. Therefore, each doctoral researcher will be co-supervised by at least two advisors.