The next lecture will be on May 28, 2025 at 2PM. We would like to extend a warm welcome to Prof. Ayami Matsushima (invited by Annette Beck-Sickinger).

Lecture: Halogen-containing environmental chemicals inhibit the binding of a coactivator for nuclear recept

The lecture will held hybrid at the Small lecture hall 117, Tallstr. 33, 04103 Leipzig and via Zoom: https://uni-leipzig.zoom-x.de/j/65593302608?pwd=bm80STBsSlJVc2ZZR2FrRkdUZU5lUT09 (Meeting-ID: 655 9330 2608, Kenncode: 141325)

PROGRAM:
1. Day: Build, grow and utilize your network.
• Defning the goal of networking
• How to map your existing network
• How to deepen already existing relationships
• How to reach out to people that don’t know you yet
• How to make networking a habit

2. Day: Increase your visibility on social media.
• Why write on social media?
• How to create content ideas
• Introduction to storytelling
• How to write headlines and „hooks“
• How to format your writing so people actually want to read
• How to build „your online community“
• Analyze what works
• How to make your social media profile more effective

PLACES AVAILABLE: 12

PARTICIPANTS: Members of SFB1423 graduate school
(everyone else will be placed on a waiting list)

REGISTRATION: email to

Twice a year all members of the SFB1423 meet for a retreat to discuss the progress of the project.

Please register here   >>>

PROGRAM:
1. Make a plan
• Goal setting: What do you want to achieve with your PhD?
• From big-picture planning to daily to-do lists
• SMART targets

2. Manage your resources
• Find your „sacred“ hours – time boxing
• Prioritizing tasks: Eisenhower Matrix
• Scheduling effective breaks and removing distraction
• Strategies to create and maintain focus
• Managing perfectionism: The pareto principle
• Know and use your superpowers
• How to create a support network

3. Dealing with crisis
• Pivoting and adapting to changes
• Knowing when to quit

PLACES AVAILABLE: 12

PARTICIPANTS: Members of SFB1423 graduate school
(everyone else will be placed on a waiting list)

REGISTRATION: email to

The workshop aims to introduce to the use of the software PyMOL to generate publication quality molecular figures. It is intended for beginners, but advanced users may benefit as well from some topics. The course material is provided as freely accessible webpages, so advanced users will easily find out if certain topics are of interest and require participation in presence or if the provided web page info suffices. We will send the web link around shortly before the course starts. In addition to generating molecular figures, PyMOL can also be used to analyze (interpret) molecular structures.

The 3-day beginner workshop will cover the following topics:
• Introduction to the PyMOL GUI
• Generation of figures: Overview, GPCR-ligand interactions
• Avoid common mistakes in showing erroneous polar interactions
• PML script files: The better way to generate and handle molecular images.
• PyMOL selection algebra
• Visualization of large complexes
• Depiction and analysis of experimental X-ray or CryoEM maps
• Superposition of molecular structures: Some points to consider
• Map properties (electrostatic potential, conservation, …) onto the protein fold or molecular surface
• Generating, analyzing and displaying AlphaFold models
• Generate simple movies
• Labeling and arranging composite figures in inkscape

The fourth day will probably be a Q&A session (if there is enough interest). So please send your questions, problems or suggestions to:

PLACES AVAILABLE: 20

PARTICIPANTS: Members of SFB1423 graduate school
(everyone else will be placed on a waiting list)

REGISTRATION: email to

Dr. Claudia Stäubert will give a short talk about his research group and his main research topics/goals.

The next lecture will be on February 11, 2025 at 3PM. We would like to extend a warm welcome to Prof. Dr. Lorenz Mitschang at the Physikalisch-Technische Bundesanstalt (PTB) (invited by Matthias Elgeti).

Lecture:
Probing hyperpolarized 129Xe-protein interaction by NMR

The lecture will held hybrid.

The next lecture will be on July 4, 2025 at 2PM. We would like to extend a warm welcome to Dr. Tobias Reiff from Heinrich-Heine-University Düsseldorf (invited by Nicole Scholz).

Lecture: 
Interorgan communication during pregnancy tunes intestinal size

The lecture will held hybrid at the RSI, Seminarroom 3 floor, Johannisalle 30, 04103 Leipzig.

Please join via Zoom: https://uni-leipzig.zoom-x.de/j/65593302608?pwd=bm80STBsSlJVc2ZZR2FrRkdUZU5lUT09 (Meeting-ID: 655 9330 2608, Kenncode: 141325)

The next lecture will be on January 9, 2025 at 11 AM. We would like to extend a warm welcome to Dr. Marjan Slak Rupnik, Full Professor of Physiology, University of Maribor. (invited by Claudia Stäubert).

Lecture:
Unraveling Nutrient and Hormonal Regulation of Pancreatic Beta Cells

The lecture will held hybrid. 

Please join via Zoom: https://uni-leipzig.zoom-x.de/j/65593302608?pwd=bm80STBsSlJVc2ZZR2FrRkdUZU5lUT09 (Meeting-ID: 655 9330 2608, Kenncode: 141325)

The next lecture will be on January 9, 2025 at 5 PM. We would like to extend a warm welcome to Dr. Daniel Matus, from the Institute of Biochemistry at the
Friedrich-Alexander-Universität Erlangen-Nürnberg (invited by Tobias Langenhan).

Lecture:
“Neuronal subtype specification in the developing nervous system by a shared temporal transcription factor sequence“

The lecture will held in person at Institut f. Biologie at the small lecture hall (room 119), Johannisallee 21, 04103 Leipzig. Please register by sending an email to .

The next lecture will be on January 6, 2025 at 11 AM. We would like to extend a warm welcome to Dr. Daniel Matus, from the Stanford University School of Medicine, USA (invited by Torsten Schöneberg).

Lecture:
“A molecular code of synapse specificity orchestrated by Adhesion GPCRs“

The lecture will held in hybrid: in person in the RSI – seminar room and via Zoom. Please register by sending an email to .

Vanderbilt-Leipzig MKF / SFB1423 Module
Computational Design and Directed Evolution of Therapeutic Peptides

Peptides as therapeutics are an emerging class of therapeutics modalities, due to their high binding affinities and specificities. Here we will discuss their characteristics as therapeutic class and give an overview on recent and future developments. Furthermore, we highlight strategies for identification and optimization of peptide therapeutics. We will also cover emerging technologies for structure-based computational design of peptides using Rosetta and new AI tools. Specifically, we will train students the theoretical background of computational techniques for peptide design and provide hands-on training with respect to engineering peptides consisting of genetically encoded but also non-canonical amino acids.

Date
December 16-20, 2024 / 1 – 5 PM

Venue
BBZ (Lecture portion virtually via Zoom)

Teacher
Prof. Allison Walker, PhD.
(Vanderbilt University, Department of Chemistry)
Prof. Annette Beck-Sickinger
(Leipzig University, Faculty for Life Science, Institute for Biochemistry)
Jun.-Prof. Dr. Christina Lamers
Jun.-Prof. Dr. Clara T. Schoeder
Prof. Dr. Leonard Kaysser
Dr. Georg Künze
(Leipzig University, Medical Faculty, Institute for Drug Discovery)

Program
>> Schedule_VULU_MKF_2024_Module.pdf

Registration
Students, postdocs, and faculty who wish to audit the class are welcome. Please register via the Online Form or send a note to Carie Fortenberry () and Anett Albrecht () as we have limited seating for the laboratory sections.

You are invited to take part on the Equality and Diversity Workshop Series. Please register here: 

13:30 – 14:30
Woman in Science – Professional Career Insight:
Dr. Anette Kaiser (Leipzig University, Medical Faculty)

15:00 – 17:00
Leadership: Principle of Arrogance for female scientists (Part 2)
Dr. med. Karin Greiner-Simank (Consultant of female leadership)

The second part of these seminars will build on the participants’ experiences and show concrete ways to gain more respect and recognition from male superiors, colleagues, customers and employees. A few tools from the Toolbox “Arrogance principle” according to Dr Peter Modler will be explained.

Register here >>>

Twice a year all members of the SFB1423 meet for a retreat to discuss the progress of the project.

Please register here   >>>

We present our Collaborativ Research Center during the annual DIES ACADEMICUS 2024 at Leipzig University.

>> Program overview

Register here >>>

Register here >>>

You are invited to take part on the Equality and Diversity Workshop Series. Please register here: 

13:30 – 14:30
Woman in Science – Professional Career Insight:
Prof. Dr. Claudia Schnohr (Leipzig University, Solid State Physics)

15:00 – 17:00
Leadership: Principle of Arrogance for female scientists (Part 1)
Dr. med. Karin Greiner-Simank (Consultant of female leadership)

In these seminars, women in management positions in all sectors can learn to understand that there are two fundamentally different communication systems in power games and turf wars: a vertical, more male-dominated system and a horizontal, more female-dominated system.

Register here >>>

Register here >>>

You are invited to take part on the Equality and Diversity Workshop Series. Please register here:

13:30 – 14:30
Woman in Science – Professional Career Insight:
PD Dr. Agnieszka Beata Kuc (HZDR, Theoretical Chemistry)

14:30 – 16:00

Plan B in Science!
Kathrin Vallund (Consultant for organizational and leadership development)

This workshop will help you to understand yourself and your career ambitions better: What is the right place for you and what do you need to perform at your best while being happy? You will learn about your personality type and the impact it has in relation to your next career steps. There will be room for exchange between the participants.

Register here >>>

As in previous years, the 27th STS Meeting will be organized as a Joint Meeting of the Signal Transduction Society with signaling study groups of the German Societies for Immunology (DGfI) and Cell Biology (DGZ), the Society for Biochemistry and Molecular Biology (GBM), the German Society for Pharmacology (DGP), and the Collaborative Research Center „Structural Dynamics of GPCR Activation and Signaling“ (SFB1423).

More information and registration:
https://sigtrans.de/meeting-2024

>> abstract submission deadline: September 1, 2024 <<

You are invited to take part on the Equality and Diversity Workshop Series. Please register here:

13:30 – 14:30
Woman in Science – Professional Career Insight:
Prof. Dr. Marlene Kretzschmer (Leipzig University, Meterology)

14:30 – 16:00

Gender Bias: How to act!
Melanie Bittner (Consultant for gender, diversity and antidiscrimination)

In 2053, 50% of professorships be held by women if gender equality in higher education progresses as it has in recent years. This workshop will give you an overview of the most important measures for diversity, equity and inclusion (DEI) at universities. You will practice recognizing and questioning common stereotypes and discuss strategies to fight gender biases.

You are invited to take part on the Equality and Diversity Workshop Series. Please register here: 

13:30 – 14:30
Woman in Science – Professional Career Insight:
Prof. Dr. Georgeta Salvan (TU Chemnitz, Semiconductor Physics)

14:30 – 16:00
Building Bridges: Cross-Cultural Communication
Dr. phil. Stephanie Rohac (Communication and organisational psychologist)

In today’s interconnected world, understanding culture and cultural differences is essential for effective communication. Culture encompasses the shared values, beliefs, norms, and practices of a group of people. It significantly influences how individuals interpret and interact with the world around them. Recognizing the impact of culture on daily communication processes is crucial for fostering meaningful interactions.

Meeting of the German Biophysics Society 2024
Please register here >>> https://dgfb2024.de/

Organized by Daniel Huster and Juliane Adler. With Special SFB1423 and GPCRs Session.

The next lecture will be on September 12. We would like to extend a warm welcome to Prof. David C. Martinelli, from the University of Connecticut, Farmington, USA (invited by Tobias Langenhan). The lecture will held in hybrid.

Lecture:
“The pleiotropic C1Q-like proteins regulate both synapses and oligodendrocyte maturation“

Zoom Link:
https://uni-leipzig.zoom.us/j/63731717253?pwd=dFcrdmxPNkFKd1FLa1JNM2JtY29NUT09

Venue:
Beckmann lecture hall
Faculty of Life Sciences
Brüderstraße 34, 04103 Leipzig

Prof. Dr. Berend Isermann will give a short talk about his research group and his main research topics/goals.

„Biased signaling via PAR-receptors“

We will have the Vanderbilt – Leipzig Symposium at Vanderbilt University, TN, USA from August 18 – 21, 2024.

If you are interesseted please send a E-Mail to .

More about the International Collaboration >>>

On behalf of Prof. Dr. Berend Isermann, we would like to cordially invite you to our next SFB1423 lecture.

Date & Venue:
June 27, 2024 at 5AM /  Room „Justus von Liebig“
(Leipzig Medical Center, House 4, (Innere und Operative Medizin), Liebigstr. 20, 04103 Leipzig)

Speaker:
Dr. Silvio Antoniak
(University of North Carolina, USA)

Title:
„Protease-dependent GPCR activation in the cardiovascular system.„

If you want to join virtually, please use the Zoom link: https://uni-leipzig.zoom-x.de/j/65593302608?pwd=bm80STBsSlJVc2ZZR2FrRkdUZU5lUT09 (Code: 141325).

On behalf of Prof. Dr. Dr. Ines Liebscher, we would like to cordially invite you to our next SFB1423 lecture.

Date & Venue:
June 20, 2024 at 3AM / Beckmann Lecture hall
(Faculty of Life Sciences, Brüderstraße 34, 04103 Leipzig)

Speaker:
Prof. Dr. Jinpeng Sun
Prof. Dr. Zhao Yang
Prof. Dr. Pengju Zhang
Zili Liu
(Shandong University, Jinan, China)

Title:
„The discovery of the subfamily of steroid hormone membrane receptors and the perception of microenvironment by GPCR“ (Sun/Yang)
„The roles and mechanisms of metabolite sensing GPCRs in cancer“ (Zhang/Liu)

If you want to join virtually, please use the Zoom link: https://uni-leipzig.zoom-x.de/j/65593302608?pwd=bm80STBsSlJVc2ZZR2FrRkdUZU5lUT09 (Code: 141325).

The next lecture will be on May 21. We would like to extend a warm welcome to Prof. Dr. Johannes W. Hell, from the University of California, UC Davis, USA (invited by Andreas Bock). The lecture will held in hybrid.

Lecture:
“Role of regulation of the Ca2+ channel CaV1.2 by b-adrenergic signaling in attention“

Zoom Link:
https://uni-leipzig.zoom.us/j/63731717253?pwd=dFcrdmxPNkFKd1FLa1JNM2JtY29NUT09

Venue:
Beckmann lecture hall
Faculty of Life Sciences
Brüderstraße 34, 04103 Leipzig

Twice a year all members of the SFB1423 meet for a retreat to discuss the progress of the project.

Please register here   >>>

The next lecture will be on February 7 from 11:30am – 1pm. We would like to extend a warm welcome to Dr. Obada Bahra from the Coskun Lab, Center of Membrane Biochemistry and Lipid Research, TU Dresden (invited by Tobias Langenhan). The lecture will held in presence.

Lecture:
„The lipid perspective of Akt signaling”

Venue:
Rudolf Schoenheimer Institute of Biochemistry
Johannisallee 30, 04103 Leipzig
Seminar Room D301/302 (3rd floor)
We are looking forward to your participation.

The 17th Leipzig Research Festival of Life Sciences takes place at the Leipzig University organized by the Faculty Of Medicine and the Faculty of Life Sciences. All young scientists can take the opportunity to present their latest research results in a public» Science Workshop «.

Awarding: 

• Young Scientist Award
• Audience Award

Opening Abstract Submission: 16.10.2023
Deadline for Abstract: 04.12.2023

Link:
https://conference.uni-leipzig.de/researchfestival/en/ 

The next lecture will be on Monday, December 18. We would like to extend a warm welcome to Prof. Dr. Christa E. Müller, from the University of Bonn and Head of Department of Pharmaceutical & Medicinal Chemistry, Pharmaceutical Institute.

Lecture: “Structural Biology-Supported Drug Development for Purinergic Targets and Orphan G Protein-Coupled Receptors“

Twice a year all members of the SFB1423 meet for a retreat to discuss the progress of the project.

Please register here   >>>

We present our Collaborativ Research Center during the annual DIES ACADEMICUS 2023 at Leipzig University.

>> Program overview

Prof. Dr. Dr. Ines Liebscher will give a short talk about her research group and here main research topics/goals.

The next lecture will be on Tuesday, October 10. We would like to extend a warm welcome to Prof. Dr. Stefanie Schirmeier, from the Technische Universität Dresden, Faculty of Biology.

Lecture: “Metabolic flexibility of the nervous system”

The Lecture will be held at the RSI, Johannisalle 30, Seminar room – 3rd floor, 04103 Leipzig.

From September 24 to 26, Alexander von Humboldt Professor and SFB1423 project leader Jens Meiler and Junior Professor Clara T. Schoeder will host a lecture series on Artificial Intelligence in Drug Development at Leipzig University.

Link:
https://europeanrosettacon.org

A key element of the summer schools will be presentation of their research by the doctoral researchers. These presentations will be given without the project leader of the project being present such that a good learning atmosphere will be created.

The next Summerschool will take place at the „Schlosshotel Schkopau“ from Septermber 11 – 13, 2023.

Please contact Juliane Adler to get more details …

Prof. Dr. Daniel Huster will give a short talk about his research group and his main research topics/goals.

„Not a GPCR, but still interesting: the specificity of lipid interactions of the intramembrane protease GlpG“

The SFB1423 will be presented in differents events at the LONG NIGHT OF SCIENCE in Leipzig: 

SFB1423 / GPCRs – Wir wollen wissen, wie sie funktionieren.
(SFB1423, BBZ, Deutscher Platz 5)

Wie Medikamente mit Rezeptoren tanzen
(Prof. Andreas Bock, Härtelstr. 16-18, SR429)

James Bond und die Physik
(Prof. Daniel Huster, Liebigstr. 13-27 GHS)

Going Deep: Künstliche Intelligenz in der Wirkstoffentwicklung
(Prof. Jens Meiler, Liebigstr. 13-27 KHS)

Pharmazeutische Wissenschaften – von der Idee zum Arzneimittel
(IfWE, BBZ, Deutscher Platz 5)

more information here >>> 

We cordially invite you to the Symposium of the Leipzig-Vanderbilt cooperation on June 9, 2023. International scientists of the Vanderbilt Diabetes Research and Training Center will talk about kidney-focused and diabetes-related research.

Ray Harris
Roy Zent
Ambra Pozzy
Ming-zhi

Venue: Small lecture hall, Talstrasse 33, ground floor
Time: 1 p.m.

MKF / SFB1423 Module
Integration of Experimental Data
with Artificial Intelligence to study
Membrane Proteins

Prof. Hassane Mchaourab
Vanderbilt University, Center for Structural Biology
Prof. Erkan Karakas
Vanderbilt University, Center for Structural Biology
Dr. Matthias Elgeti and Prof. Dr. Jens Meiler
Leipzig University, Faculty of Medicine

>> Click here to get the Program

Registration
Please send an Email to
.

More details will be announced shortly. 

The next lecture will be on Thursday, May 25 from 4:30 – 6:30 PM. We would like to extend a warm welcome to Prof. Steffen Lindert, from the Columbia University, The Ohio State University, Dep. Of Chemistry and Biochemistry, USA with his lecture:

“COMPUTATIONAL PROTEIN STRUCTURE PREDICTION
FROM MASS SPECTROMETRY DATA”

You can join the lecture in person at the Charles Tanford Protein Centre, Halle (Saale), Seminar room E.04.0 or online via zoom (link will follow soon)

Twice a year all members of the SFB1423 meet for a retreat to discuss the progress of the project.

Please register here >> 

Prof. Dr. Tosten Schöneberg will give a short talk about his research group and his main research topics/goals.

„GPCR dysfunctions as causes of human pathologies“

The next lecture will be on Tuesday, April 4 from 2 – 3 PM. We would like to extend a warm welcome to Prof. Jonathan A. Javitch,, from the Columbia University, Department of Molecular Pharmacology and Therapeutics and Department of Psychiatry, USA with his lecture:

“My recent forays into adhesion GPCRs: what has stuck”

You can join the lecture in person at the Seminar Room (3rd floor), Rudolf Schönheimer Institute of Biochemistry, Leipzig.

Prof. Dr. Peter Hildebrand will give a short talk about his research group and his main research topics/goals.

„Structural mechanism of Gs protein activation by the prototypical beta-2 adrenergic receptor“

SFB1423/MKF Seminar:
Current Developments in Experimental and Computational engineering of Peptide Therapeutics

Peptides as therapeutics are an emerging class of therapeutics modalities, due to their high binding affinities and specificities. Here we will discuss their characteristics as therapeutic class and give an overview on recent and future developments. Furthermore, we highlight strategies for identification and optimization of peptide therapeutics. We will also cover emerging technologies for structure-based computational design of peptides using Rosetta. Specifically, we will train students in the theoretical background of computational techniques for Peptide design and provide hands-on training with respect to engineering peptides consisting of genetically encoded but also non-canonical amino acids.

Prof. Christina Lamers & Prof. Annette Beck-Sickinger (Leipzig University)

Prof. Allison Walker, Prof. Rocco Moretti and Prof. Benjamin P. Brown (Vanderbilt University) 

Registration via email to Juliane Adler

The next lecture will be on Monday, February 13 from 4 – 5 PM. We would like to extend a warm welcome to Prof. Asuka Inoue, from the Tohoku University, Japan with his lecture:

“How to dissect complexity of GPCR signaling?”

You can join the lecture in person at the Institute of Biochemistry, Small Lecture Hall, Brüderstraße 34 in Leipzig or you dial-in via Zoom link:

https://uni-leipzig.zoom.us/j/67824242189?pwd=eVo3VWppVEF6Vjd0U3lmZnoxSTlGQT09

(Meeting-ID: 678 2424 2189 / Kenncode: 250088)

The next lecture will be on Friday, January 13 from 9 – 10 AM. We would like to extend a warm welcome to Prof. Carsten Hoffmann from the Institute for Molecular Cell Biology of the University Hospital Jena with his lecture:

“GRK Knock-out cells reveal new insights into GPCR regulation”

You can join the lecture in person at the Institute of Biophysics, Lecture Hall (big), Härtelstraße 16/18 in Leipzig or you dial-in via Zoom link:
https://uni-leipzig.zoom.us/j/63261926503?pwd=cEwzSGVxYTJzY29NQUFscTd2OGtzZz09

On Thursday, January 12 from 9:15 – 10:15 AM Mr Fabian Pohl from the BBZ Leipzig, Sträter Lab will give a lecture at the Rudolf Schoenheimer Institute of Biochemistry on the topic:

“Structural Characterization of the Autoproteolysis and Dimerization Behavior of ADGRB2”.

You can join the lecture in person at the Rudolf Schoenheimer Institute of Biochemistry, Seminar Room D301/302 (3rd floor), Johannisallee 30 in Leipzig.