How mechanical stimuli trigger cellular signalling
Prof. Dr. Dr. Ines Liebscher. Foto: Swen Reichhold

How mechanical stimuli trigger cellular signalling

International GPCR research collaboration deciphers structure of active receptors  (Press release 2022/072 from 14/04/2022, written by Peggy Darius) Breathing, seeing, hearing – the family of G protein-coupled receptors (GPCRs) is involved in a variety of physiological processes and is also the cause of diverse diseases. As…

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Season´s Greetings

Dear friends of the SFB1423, The whole team of the SFB1423 wishes you MERRY CHRISTMAS and a HAPPY and HEALTHY NEW YEAR 2022! We want to thank you for the constructive and pleasant cooperation. Stay safe and we are looking forwards to another year full…

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4GPCRnet – International Symposium

We cordially invite you to the 4GPCRnet International Symposium that will take place September 26-29, 2022 in Leipzig, Germany. The event is organized by four of the largest European networks in the field of GPCR research: the COST Actions Adher’n Rise and ERNEST, and the DFG-funded collaborative projects SFB1423 “Structural Dynamics of GPCR Activation…

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Insight into the molecular structure of an appetite-regulating cell receptor

New joint Publication by subproject A01, A05, Z03, B02 and C01/Z04:  Activation of the G-protein-coupled MC4R receptor by the drug setmelanotide. The image shows how the hormone combines with the receptor to activate the G-protein. The receptor then causes the GDP nucleotide to split from…

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1st virtual Summer School of the Graduate School

We are happy to announce the first version of the CRC1423 Summer School held from September 14-18, 2020. The meeting takes place virtually. Please find below the program and further information.  Program  Registration We strongly encourage early career scientists (PhDs) to register. Please send an…

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Award for new research projects

[JANUARY 09, 2020 / CHRISTINA ANDERS / MDC News ] The DFG is funding two new research projects at the MDC: More than half a million euros will be available to researchers* to study signalling processes of receptors. Without them we would not be able…

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