Hederagenin blocks the activation of the neuropeptide FF receptor 1, a protein found mainly in the spinal cord and areas of the brain involved in pain perception. Graphic: Hannah Lentschat
On January 30, 2025, the 18th Research Festival for Life Sciences took place at Leipzig University. Every year, the event provides a platform for young scientists from the fields of medicine and life sciences to present their research to an expert audience. This year, 190…
Hederagenin blocks the activation of the neuropeptide FF receptor 1, a protein found mainly in the spinal cord and areas of the brain involved in pain perception. Graphic: Hannah Lentschat
Hederagenin blocks the activation of the neuropeptide FF receptor 1, a protein found mainly in the spinal cord and areas of the brain involved in pain perception. Graphic: Hannah Lentschat
This year's Poster Awards of the SFB1423 goes to: Robin Schick (A06) Modulating factors and kinetics of GAIN cleavage Luisa Buhl & Lisa Kupsch (B05) Characterization of GPR133/ADGRD1 mediated signaling Pauline Löffler (C08) Towards monitoring conformational dynamics of GPCRs on single-molecule level The SFB1423 awards…
This year's doctoral prizes in the life sciences went to 2 outstanding researchers at the Institute of Biochemistry of the Faculty of Life Sciences. Dr. Corinna Schüß was awarded for her dissertation “Exploring the Neuropeptide Y4 Receptor from an Orthosteric and Allosteric Perspective” (submitted in…
Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A key modern approach is genetic code expansion (GCE), which makes it possible to modify proteins directly in living cells to give them tailor-made properties. Professor Irene…
[21.10.24 written by Patrick Scheerer] Professor Klaus-Peter Hofmann, a leading biochemist and biophysicist, revolutionized our understanding of visual signal transduction through his research on rhodopsin and G protein-coupled receptors. His work laid the foundation for advances in cellular biology and drug development, leaving a lasting…
This year's GBD Master's Prize was awarded to Tim Pelczyk forhis thesis “Comparative characterization of the binding modes of the hexapeptide UR-AK86c and the endogenous ligand PP at Y4R by mutagenesis studies”. The thesis was written as part of the SFB1423 project “Molecular mechanisms of…
The Meeting of the German Biophysical Society 2024 - organized by Prof. Dr. Daniel Huster (Project leader of A04 and IRGT) and Dr. Juliane Adler (Coordinator of the IRTG) took place from September 22 to 25 at the Campus Augustplatz in Leipzig. The organization team…