Naturally occurring hederagenin binds to pain regulation receptor

Hederagenin blocks the activation of the neuropeptide FF receptor 1, a protein found mainly in the spinal cord and areas of the brain involved in pain perception. Graphic: Hannah Lentschat

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SFB1423 Retreat: Poster Awards for Luisa Buhl, Pauline Löffler and Robin Schick

This year's Poster Awards of the SFB1423 goes to: Robin Schick (A06)  Modulating factors and kinetics of GAIN cleavage Luisa Buhl & Lisa Kupsch (B05) Characterization of GPR133/ADGRD1 mediated signaling Pauline Löffler (C08)  Towards monitoring conformational dynamics of GPCRs on single-molecule level The SFB1423 awards…

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Best dissertations in life sciences: Corinna Schüss (2022) and Anne Czerniak (2023)
Vier der sieben Preisträger:innen (Dr. Alexandra Brakel, Dr. Anne Sophie Czerniak, Dr. Corinna Schüß und Felix Hagemeyer, v.l.n.r.) wurde der Promotionspreis der Universität Leipzig zum Tag der Promotion in der Villa Tillmanns verliehen. Foto: Christian Hüller

Best dissertations in life sciences: Corinna Schüss (2022) and Anne Czerniak (2023)

This year's doctoral prizes in the life sciences went to 2 outstanding researchers at the Institute of Biochemistry of the Faculty of Life Sciences.  Dr. Corinna Schüß was awarded for her dissertation “Exploring the Neuropeptide Y4 Receptor from an Orthosteric and Allosteric Perspective” (submitted in…

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Blue Flame Award for Professor Irene Coin’s lab
Professor Irene Coin and Dr Robert Serfling with their Blue Flame Award. Photo: Christian Hüller, Leipzig University

Blue Flame Award for Professor Irene Coin’s lab

Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A key modern approach is genetic code expansion (GCE), which makes it possible to modify proteins directly in living cells to give them tailor-made properties. Professor Irene…

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A Pioneer in Visual Signal Transduction: In Memory of Professor Klaus-Peter Hofmann (1943–2024)

[21.10.24 written by Patrick Scheerer] Professor Klaus-Peter Hofmann, a leading biochemist and biophysicist, revolutionized our understanding of visual signal transduction through his research on rhodopsin and G protein-coupled receptors. His work laid the foundation for advances in cellular biology and drug development, leaving a lasting…

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GBM Master Prize: Tim Pelczyk for SFB1423 subproject B01

This year's GBD Master's Prize was awarded to Tim Pelczyk forhis thesis “Comparative characterization of the binding modes of the hexapeptide UR-AK86c and the endogenous ligand PP at Y4R by mutagenesis studies”. The thesis was written as part of the SFB1423 project “Molecular mechanisms of…

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Special SFB1423 & GPCR Session within the German Biophysical Society Meeting 2024 in Leipzig (September 22-25, 2024)

The Meeting of the German Biophysical Society 2024 - organized by Prof. Dr. Daniel Huster (Project leader of A04 and IRGT) and Dr. Juliane Adler (Coordinator of the IRTG) took place from September 22 to 25 at the Campus Augustplatz in Leipzig. The organization team…

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Investigating new molecular switch in human diseases: Professor Berend Isermann awarded ERC Advanced Grant

[Press release Leipzig University 2024/138 from 11/09/2024 by Anne Grimm] Professor Berend Isermann (Project leader of the SFB1423 subproject C07) has been awarded an ERC Advanced Grant by the European Research Council in recognition of the high relevance of his scientific work. The award is…

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15th Anniversary of Leipzig-Vanderbilt Connection in Research and Education

In 2009 the heads of both universities signed a „Memorandum of Understanding“ (MOU), extended 2013 and 2018 that remain in force until 2028. The MOU allows and encourages academic exchanges between both universities; facilitate joint research programs, student programs, and a cultural exchange program. This…

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Andreas Bock is new director of the Institute of Pharmacology at Mainz University Medical Center

[Press release Unimedizin-Mainz.de from 29.07.2024 by Veronika Wagner] Prof. Dr. Andreas Bock will head the Institute of Pharmacology at the Mainz University Medical Center from August 1, 2024. The pharmacist will also take over the W3 professorship for pharmacology as the successor to Professor Dr. Ulrich…

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