How mechanical stimuli trigger cellular signalling
Prof. Dr. Dr. Ines Liebscher. Foto: Swen Reichhold

How mechanical stimuli trigger cellular signalling

International GPCR research collaboration deciphers structure of active receptors  (Press release 2022/072 from 14/04/2022, written by Peggy Darius) Breathing, seeing, hearing – the family of G protein-coupled receptors (GPCRs) is involved in a variety of physiological processes and is also the cause of diverse diseases. As…

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New SFB1423 publications available

At the end of a long research work is the publication of their results. Be amazed and read them yourself.Catar R, Herse-Naether M, Zhu N, Wagner P, Wischnewski O, Kusch A, Kamhieh-Milz J, Eisenreich A, Rauch U, Hegner B, Heidecke H, Kill A, Riemekasten G,…

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Season´s Greetings

Dear friends of the SFB1423, The whole team of the SFB1423 wishes you MERRY CHRISTMAS and a HAPPY and HEALTHY NEW YEAR 2022! We want to thank you for the constructive and pleasant cooperation. Stay safe and we are looking forwards to another year full…

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4GPCRnet – International Symposium

We cordially invite you to the 4GPCRnet International Symposium that will take place September 26-29, 2022 in Leipzig, Germany. The event is organized by four of the largest European networks in the field of GPCR research: the COST Actions Adher’n Rise and ERNEST, and the DFG-funded collaborative projects SFB1423 “Structural Dynamics of GPCR Activation…

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Insight into the molecular structure of an appetite-regulating cell receptor

New joint Publication by subproject A01, A05, Z03, B02 and C01/Z04:  Activation of the G-protein-coupled MC4R receptor by the drug setmelanotide. The image shows how the hormone combines with the receptor to activate the G-protein. The receptor then causes the GDP nucleotide to split from…

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Scientific Module – Exploring Biomolecules in 3D

We cordially invite you to a one week block online seminar “Exploring Biomolecules in 3D: Principles and Applications of Computational Structural Biology” by: Prof. Dr. Jens Meiler (Leipzig University, Coordinator) Dr. Georg Kuenze (Leipzig University) Prof. Dr. Jarrod Smith (Vanderbilt University / USA) Prof. Dr. Rocco Moretti (Vanderbilt University…

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